USP13 promotes enzalutamide resistance by catalyzing depolyubiquitination of PCMT1 in prostate cancer.

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Title: USP13 promotes enzalutamide resistance by catalyzing depolyubiquitination of PCMT1 in prostate cancer.
Authors: Wang Z; Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.; Jiangxi Institute of Urology, Nanchang, China.; Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, China., Liu X; Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.; Jiangxi Institute of Urology, Nanchang, China., Li Z; Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.; Jiangxi Institute of Urology, Nanchang, China., Yuan R; Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.; Jiangxi Institute of Urology, Nanchang, China., Zheng F; Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.; Jiangxi Institute of Urology, Nanchang, China., Xiong S; Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.; Jiangxi Institute of Urology, Nanchang, China., Zeng J; Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.; Jiangxi Institute of Urology, Nanchang, China., Pang W; College of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, China., Fu B; Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.; Jiangxi Institute of Urology, Nanchang, China., Li S; Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China. aflypig09@163.com.; Jiangxi Institute of Urology, Nanchang, China. aflypig09@163.com., Xu S; Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China. ndyfy10021@ncu.edu.cn.; Jiangxi Institute of Urology, Nanchang, China. ndyfy10021@ncu.edu.cn., Deng J; Department of Urology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China. dengjun2004@163.com.; Jiangxi Institute of Urology, Nanchang, China. dengjun2004@163.com.
Source: Cell death & disease [Cell Death Dis] 2026 Apr 30; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-4889
DOI:10.1038/s41419-026-08824-9