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The lactate-lactylation axis in acute kidney injury: mechanisms from metabolic reprogramming to epigenetic regulation and clinical therapeutic prospects.

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Bibliographic Details
Title: The lactate-lactylation axis in acute kidney injury: mechanisms from metabolic reprogramming to epigenetic regulation and clinical therapeutic prospects.
Authors: Chen J; Department of Nephrology, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, No.13, Shi Liu Gang Road, Guangzhou, 510315, Guangdong, China.; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China., Zhang Y; Department of Nephrology, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, No.13, Shi Liu Gang Road, Guangzhou, 510315, Guangdong, China.; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China., Ni S; Department of Nephrology, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, No.13, Shi Liu Gang Road, Guangzhou, 510315, Guangdong, China.; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China., Qi J; Department of Nephrology, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, No.13, Shi Liu Gang Road, Guangzhou, 510315, Guangdong, China.; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China., Mo Y; Department of Nephrology, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, No.13, Shi Liu Gang Road, Guangzhou, 510315, Guangdong, China. moyenan@126.com., Nie X; Department of Nephrology, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, No.13, Shi Liu Gang Road, Guangzhou, 510315, Guangdong, China. nxl117@163.com.
Source: International urology and nephrology [Int Urol Nephrol] 2026 Apr 29. Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0262521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2584 (Electronic) Linking ISSN: 03011623 NLM ISO Abbreviation: Int Urol Nephrol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-2584
DOI:10.1007/s11255-026-05168-3