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Licochalcone E Ameliorates Hepatic Steatosis in Obese Mice by Activating the Sirt1/AMPK Pathway and Reducing Hepatic Lipid Accumulation.

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Title: Licochalcone E Ameliorates Hepatic Steatosis in Obese Mice by Activating the Sirt1/AMPK Pathway and Reducing Hepatic Lipid Accumulation.
Authors: Huang WC; Graduate Institute of Health Industry Technology, Center for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan.; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan City 33378, Taiwan.; Department of Pediatrics, New Taipei Municipal TuCheng Hospital (Built and Operated by Chang Gung Medical Foundation), New Taipei 23656, Taiwan., Wu SJ; Department of Nutrition and Health Sciences, Center for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan.; Aesthetic Medical Center, Department of Dermatology, Chang Gung Memorial Hospital, Taoyuan 33342, Taiwan., Liu XM; Graduate Institute of Health Industry Technology, Center for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan., Cheng SC; Graduate Institute of Health Industry Technology, Center for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan.; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan City 33378, Taiwan., Lin PT; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33303, Taiwan.; Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Taoyuan City 33342, Taiwan., Kuo CL; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan City 33378, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33303, Taiwan., Liou CJ; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan City 33378, Taiwan.; Department of Nursing, Division of Basic Medical Sciences, Center for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan.
Source: Biomolecules & therapeutics [Biomol Ther (Seoul)] 2026 May 01; Vol. 34 (3), pp. 676-688. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Korean Society of Applied Pharmacology Country of Publication: Korea (South) NLM ID: 101472832 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1976-9148 (Print) Linking ISSN: 19769148 NLM ISO Abbreviation: Biomol Ther (Seoul) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Licochalcone E Ameliorates Hepatic Steatosis in Obese Mice by Activating the Sirt1/AMPK Pathway and Reducing Hepatic Lipid Accumulation.
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  Data: <searchLink fieldCode="AU" term="%22Huang+WC%22">Huang WC</searchLink>; Graduate Institute of Health Industry Technology, Center for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan.; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan City 33378, Taiwan.; Department of Pediatrics, New Taipei Municipal TuCheng Hospital (Built and Operated by Chang Gung Medical Foundation), New Taipei 23656, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+SJ%22">Wu SJ</searchLink>; Department of Nutrition and Health Sciences, Center for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan.; Aesthetic Medical Center, Department of Dermatology, Chang Gung Memorial Hospital, Taoyuan 33342, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+XM%22">Liu XM</searchLink>; Graduate Institute of Health Industry Technology, Center for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+SC%22">Cheng SC</searchLink>; Graduate Institute of Health Industry Technology, Center for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan.; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan City 33378, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+PT%22">Lin PT</searchLink>; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33303, Taiwan.; Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Taoyuan City 33342, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+CL%22">Kuo CL</searchLink>; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan City 33378, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33303, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liou+CJ%22">Liou CJ</searchLink>; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan City 33378, Taiwan.; Department of Nursing, Division of Basic Medical Sciences, Center for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101472832%22">Biomolecules & therapeutics</searchLink> [Biomol Ther (Seoul)] 2026 May 01; Vol. 34 (3), pp. 676-688. <i>Date of Electronic Publication: </i>2026 Apr 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Korean+Society+of+Applied+Pharmacology%22">Korean Society of Applied Pharmacology </searchLink><i>Country of Publication: </i>Korea (South) <i>NLM ID: </i>101472832 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1976-9148 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219769148%22">19769148 </searchLink><i>NLM ISO Abbreviation: </i>Biomol Ther (Seoul) <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.4062/biomolther.2025.162
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        Text: English
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      – TitleFull: Licochalcone E Ameliorates Hepatic Steatosis in Obese Mice by Activating the Sirt1/AMPK Pathway and Reducing Hepatic Lipid Accumulation.
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              Text: 2026 May 01
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