Gene syntax defines supercoiling-mediated transcriptional feedback.
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| Title: | Gene syntax defines supercoiling-mediated transcriptional feedback. |
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| Authors: | Johnstone CP; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Love KS; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Kabaria SR; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Jones RD; School of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada.; Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada., Blanch-Asensio A; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Ploessl DS; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Peterman EL; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Lee R; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Yun J; School of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada.; Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada., Oakes CG; Department of Bioengineering, California Institute of Technology, Pasadena, CA, USA., Mummery CL; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Leiden University Medical Center, Leiden, Netherlands., Davis RP; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Leiden University Medical Center, Leiden, Netherlands., DeKosky BJ; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; The Ragon Institute of Mass General, MIT, and Harvard, Cambridge, MA, USA., Zandstra PW; School of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada.; Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada., Galloway KE; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. |
| Source: | Science (New York, N.Y.) [Science] 2026 Apr 30; Vol. 392 (6797), pp. eadw1925. Date of Electronic Publication: 2026 Apr 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.adw1925 |
