Toward life with a 19-amino acid alphabet through generative artificial intelligence design.
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| Title: | Toward life with a 19-amino acid alphabet through generative artificial intelligence design. |
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| Authors: | Liu L; Department of Systems Biology, Columbia University, New York, NY, USA., Rochereau C; Department of Systems Biology, Columbia University, New York, NY, USA.; Integrated Program in Cellular, Molecular, and Biomedical Studies, Columbia University, New York, NY, USA., Kozlov S; Faculty of Arts and Sciences, Harvard University, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Urtecho G; Department of Systems Biology, Columbia University, New York, NY, USA., Liu X; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biostatistics, Harvard University, Cambridge, MA, USA., Zhao J; Department of Systems Biology, Columbia University, New York, NY, USA., Wang J; Department of Systems Biology, Columbia University, New York, NY, USA., Huang Y; Department of Systems Biology, Columbia University, New York, NY, USA., Qu Y; Department of Systems Biology, Columbia University, New York, NY, USA., Zhang Z; Department of Systems Biology, Columbia University, New York, NY, USA.; Department of Biomedical Engineering, Columbia University, New York, NY, USA., Blazejewski T; Department of Systems Biology, Columbia University, New York, NY, USA.; Integrated Program in Cellular, Molecular, and Biomedical Studies, Columbia University, New York, NY, USA., Swartz A; Faculty of Arts and Sciences, Harvard University, Cambridge, MA, USA., Ovchinnikov S; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; John Harvard Distinguished Science Fellowship, Harvard University, Cambridge, MA, USA., Wang HH; Department of Systems Biology, Columbia University, New York, NY, USA.; Department of Biomedical Engineering, Columbia University, New York, NY, USA.; Department of Pathology and Cell Biology, Columbia University, New York, NY, USA. |
| Source: | Science (New York, N.Y.) [Science] 2026 Apr 30; Vol. 392 (6797), pp. eaeb5171. Date of Electronic Publication: 2026 Apr 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.aeb5171 |
