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From acute infection to chronic osteoimmune remodeling: immunopathogenesis and precision immunotherapeutic strategies in osteomyelitis.

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Title: From acute infection to chronic osteoimmune remodeling: immunopathogenesis and precision immunotherapeutic strategies in osteomyelitis.
Authors: Wei SQ; Department of Trauma Emergency Center, Ganzhou People's Hospital, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Trauma Emergency Center, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Trauma Emergency Center, Affiliated Ganzhou Hospital, Jiangxi Medical College, Nanchang University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Ganzhou City Key Laboratory of Bone Metabolism, Ganzhou, 341000, Jiangxi Province, PR China., Guo C; Department of Spine Surgery, Ganzhou People's Hospital, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Spine Surgery, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Spine Surgery, Affiliated Ganzhou Hospital, Jiangxi Medical College, Nanchang University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China., Lu ZJ; Department of Spine Surgery, Ganzhou People's Hospital, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Spine Surgery, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Spine Surgery, Affiliated Ganzhou Hospital, Jiangxi Medical College, Nanchang University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China., Lin FX; Department of Spine Surgery, Ganzhou People's Hospital, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Spine Surgery, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Spine Surgery, Affiliated Ganzhou Hospital, Jiangxi Medical College, Nanchang University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China. Electronic address: feixianglin0@sina.com.
Source: International immunopharmacology [Int Immunopharmacol] 2026 Jul 15; Vol. 181, pp. 116669. Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: From acute infection to chronic osteoimmune remodeling: immunopathogenesis and precision immunotherapeutic strategies in osteomyelitis.
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  Data: <searchLink fieldCode="AU" term="%22Wei+SQ%22">Wei SQ</searchLink>; Department of Trauma Emergency Center, Ganzhou People's Hospital, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Trauma Emergency Center, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Trauma Emergency Center, Affiliated Ganzhou Hospital, Jiangxi Medical College, Nanchang University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Ganzhou City Key Laboratory of Bone Metabolism, Ganzhou, 341000, Jiangxi Province, PR China.<br /><searchLink fieldCode="AU" term="%22Guo+C%22">Guo C</searchLink>; Department of Spine Surgery, Ganzhou People's Hospital, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Spine Surgery, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Spine Surgery, Affiliated Ganzhou Hospital, Jiangxi Medical College, Nanchang University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China.<br /><searchLink fieldCode="AU" term="%22Lu+ZJ%22">Lu ZJ</searchLink>; Department of Spine Surgery, Ganzhou People's Hospital, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Spine Surgery, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Spine Surgery, Affiliated Ganzhou Hospital, Jiangxi Medical College, Nanchang University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China.<br /><searchLink fieldCode="AU" term="%22Lin+FX%22">Lin FX</searchLink>; Department of Spine Surgery, Ganzhou People's Hospital, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Spine Surgery, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China; Department of Spine Surgery, Affiliated Ganzhou Hospital, Jiangxi Medical College, Nanchang University, 16 Meiguan Avenue, Ganzhou, Jiangxi Province 341000, PR China. Electronic address: feixianglin0@sina.com.
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  Data: <searchLink fieldCode="JN" term="%22100965259%22">International immunopharmacology</searchLink> [Int Immunopharmacol] 2026 Jul 15; Vol. 181, pp. 116669. <i>Date of Electronic Publication: </i>2026 Apr 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>100965259 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-1705 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215675769%22">15675769 </searchLink><i>NLM ISO Abbreviation: </i>Int Immunopharmacol <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.intimp.2026.116669
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      – Code: eng
        Text: English
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        StartPage: 116669
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      – TitleFull: From acute infection to chronic osteoimmune remodeling: immunopathogenesis and precision immunotherapeutic strategies in osteomyelitis.
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            NameFull: Wei SQ
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            NameFull: Guo C
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            NameFull: Lu ZJ
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            – D: 15
              M: 07
              Text: 2026 Jul 15
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1878-1705
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              Value: 181
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            – TitleFull: International immunopharmacology
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