On-treatment serum prostate-specific antigen and overall survival in prostate cancer (STAMPEDE platform protocol): a post-hoc analysis of data from five phase 3 trials.

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Title: On-treatment serum prostate-specific antigen and overall survival in prostate cancer (STAMPEDE platform protocol): a post-hoc analysis of data from five phase 3 trials.
Authors: Kayani M; UCL Cancer Institute, University College London, London, UK; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK; Department of Oncology, University College London Hospitals, London, UK., Murphy L; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., Dutey-Magni P; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., Howlett S; UCL Cancer Institute, University College London, London, UK; Department of Oncology, University College London Hospitals, London, UK., Sachdeva A; Division of Cancer Sciences, University of Manchester, Manchester, UK; Department of Surgery, Christie NHS Foundation Trust, Manchester, UK., Padden-Modi M; Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, UK., Abdel-Aty H; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK; Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, UK., Brown LC; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., Amos CL; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., Chan K; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., Gilbert DC; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., Langley RE; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., Brown M; Division of Cancer Sciences, University of Manchester, Manchester, UK., Sydes MR; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., Parker CC; Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, UK., Cross W; St James's University Hospital, Leeds, UK., Malik Z; Clatterbridge Cancer Centre NHS Foundation Trust, Wirral, UK., Varughese M; Royal Devon University Healthcare NHS Foundation Trust and University of Exeter, UK., Turco F; Institute of Oncology of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland and Faculty of Biosciences, University of Southern Switzerland, Lugano, Switzerland., Millman R; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., Matheson D; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., Gillessen S; Institute of Oncology of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland and Faculty of Biosciences, University of Southern Switzerland, Lugano, Switzerland., Clarke NW; Division of Cancer Sciences, University of Manchester, Manchester, UK; Department of Surgery, Christie NHS Foundation Trust, Manchester, UK; Department of Urology, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK., Parmar MKB; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., James ND; Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, UK., Attard G; UCL Cancer Institute, University College London, London, UK; Department of Oncology, University College London Hospitals, London, UK. Electronic address: g.attard@ucl.ac.uk.
Corporate Authors: STAMPEDE Collaborators
Source: The Lancet. Oncology [Lancet Oncol] 2026 May; Vol. 27 (5), pp. 625-636.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1474-5488
DOI:10.1016/S1470-2045(26)00066-5