Artificial intelligence-driven donor-recipient gut microbiome matching for optimized fecal microbiota transplantation.

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Title: Artificial intelligence-driven donor-recipient gut microbiome matching for optimized fecal microbiota transplantation.
Authors: Su Q; Microbiota I-Center (MagIC), Hong Kong SAR, China; Department of Medicine and Therapeutics, State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Chen S; Microbiota I-Center (MagIC), Hong Kong SAR, China; Department of Medicine and Therapeutics, State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Lau LH; Department of Medicine and Therapeutics, State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Lui RN; Department of Medicine and Therapeutics, State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Wang Y; Microbiota I-Center (MagIC), Hong Kong SAR, China; Department of Medicine and Therapeutics, State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Xu Z; Microbiota I-Center (MagIC), Hong Kong SAR, China; Department of Medicine and Therapeutics, State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Cheung CP; Microbiota I-Center (MagIC), Hong Kong SAR, China; Department of Medicine and Therapeutics, State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Ching JYL; Microbiota I-Center (MagIC), Hong Kong SAR, China; Department of Medicine and Therapeutics, State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Shen X; Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore 639798, the Republic of Singapore; School of Chemistry, Chemical Engineering, and Biotechnology, Nanyang Technological University Singapore, Singapore 649798, the Republic of Singapore., Peng Y; Microbiota I-Center (MagIC), Hong Kong SAR, China; JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR 999077, China; Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR 999077, China., Tun HM; Microbiota I-Center (MagIC), Hong Kong SAR, China; JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR 999077, China; Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR 999077, China., Ianiro G; Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome, Italy; Department of Medical and Surgical Sciences, UOC Gastroenterologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Department of Medical and Surgical Sciences, UOC CEMAD Centro Malattie dell'Apparato Digerente, Medicina Interna e Gastroenterologia, Fondazione Policlinico Universitario Gemelli IRCCS, Rome, Italy., Rubin D; University of Chicago, Department of Medicine, Section of Gastroenterology, Hepatology and Nutrition, Chicago, IL, USA., Chang EB; University of Chicago, Department of Medicine, Section of Gastroenterology, Hepatology and Nutrition, Chicago, IL, USA., Chan FKL; Microbiota I-Center (MagIC), Hong Kong SAR, China; Centre for Gut Microbiota Research, The Chinese University of Hong Kong, Hong Kong SAR, China; The D.H. Chen Foundation Hub of Advanced Technology for Child Health (HATCH), The Chinese University of Hong Kong, Hong Kong SAR, China; Li Ka Shing Institute of Health Sciences, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong SAR, China. Electronic address: fklchan@cuhk.edu.hk., Ng SC; Microbiota I-Center (MagIC), Hong Kong SAR, China; Department of Medicine and Therapeutics, State Key Laboratory of Digestive Diseases, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China; New Cornerstone Science Laboratory, The Chinese University of Hong Kong, Hong Kong, China. Electronic address: siewchienng@cuhk.edu.hk.
Source: Cell reports [Cell Rep] 2026 May 26; Vol. 45 (5), pp. 117301. Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2026.117301