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Upping the "Plex": Whole Slide, Automated 14-Color Multiplex Immunofluorescence Staining of the Tumor Microenvironment in Paraffin-Embedded Tissue.

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Title: Upping the "Plex": Whole Slide, Automated 14-Color Multiplex Immunofluorescence Staining of the Tumor Microenvironment in Paraffin-Embedded Tissue.
Authors: Lai J; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Cavagnini KS; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Smith M; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Katemboh K; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Sunshine JC; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; The Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Taube JM; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; The Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: jtaube1@jhmi.edu., Engle LL; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; The Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, Maryland; The Mark Foundation Center for Advanced Genomics and Imaging, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Source: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2026 Jun; Vol. 106 (6), pp. 106130. Date of Electronic Publication: 2026 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0376617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0307 (Electronic) Linking ISSN: 00236837 NLM ISO Abbreviation: Lab Invest Subsets: MEDLINE
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        Value: 10.1016/j.labinv.2026.106130
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      – TitleFull: Upping the "Plex": Whole Slide, Automated 14-Color Multiplex Immunofluorescence Staining of the Tumor Microenvironment in Paraffin-Embedded Tissue.
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              Text: 2026 Jun
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