Pharmacokinetic Drug-Drug Interaction of Leritrelvir in Healthy Chinese Volunteers: A Single-Arm, Open-Label, Dual-Cohort Study.

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Title: Pharmacokinetic Drug-Drug Interaction of Leritrelvir in Healthy Chinese Volunteers: A Single-Arm, Open-Label, Dual-Cohort Study.
Authors: Peng J; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China.; Drug Clinical Trial Institution, Guangzhou Chest Hospital, Institute of Tuberculosis, Guangzhou Medical University, Guangzhou, China., Chen J; Drug Clinical Trial Institution, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Du XX; Drug Clinical Trial Institution, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Li HJ; Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, China.; Guangdong Raynovent Biotechnology Co., Ltd., Guangzhou, China., Qin RZ; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Chen SH; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Liu X; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Cheng Q; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Li XM; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Huang DX; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Duan L; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Li MY; Department of Cardiology, Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Wu WZ; Department of Urology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Ye LK; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Li YY; Guangdong Raynovent Biotechnology Co., Ltd., Guangzhou, China., Xie ZH; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China. xzh0302@126.com., Han K; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China. cjy-ke@163.com.; Drug Clinical Trial Institution, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. cjy-ke@163.com.
Source: Clinical drug investigation [Clin Drug Investig] 2026 Jun; Vol. 46 (6), pp. 609-618. Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9504817 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1918 (Electronic) Linking ISSN: 11732563 NLM ISO Abbreviation: Clin Drug Investig Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1179-1918
DOI:10.1007/s40261-026-01556-w