Pharmacokinetic Drug-Drug Interaction of Leritrelvir in Healthy Chinese Volunteers: A Single-Arm, Open-Label, Dual-Cohort Study.
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| Title: | Pharmacokinetic Drug-Drug Interaction of Leritrelvir in Healthy Chinese Volunteers: A Single-Arm, Open-Label, Dual-Cohort Study. |
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| Authors: | Peng J; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China.; Drug Clinical Trial Institution, Guangzhou Chest Hospital, Institute of Tuberculosis, Guangzhou Medical University, Guangzhou, China., Chen J; Drug Clinical Trial Institution, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Du XX; Drug Clinical Trial Institution, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Li HJ; Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, China.; Guangdong Raynovent Biotechnology Co., Ltd., Guangzhou, China., Qin RZ; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Chen SH; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Liu X; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Cheng Q; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Li XM; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Huang DX; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Duan L; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Li MY; Department of Cardiology, Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Wu WZ; Department of Urology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Ye LK; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China., Li YY; Guangdong Raynovent Biotechnology Co., Ltd., Guangzhou, China., Xie ZH; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China. xzh0302@126.com., Han K; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China. cjy-ke@163.com.; Drug Clinical Trial Institution, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. cjy-ke@163.com. |
| Source: | Clinical drug investigation [Clin Drug Investig] 2026 Jun; Vol. 46 (6), pp. 609-618. Date of Electronic Publication: 2026 May 01. |
| Publication Type: | Journal Article; Clinical Trial, Phase I |
| Journal Info: | Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9504817 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1918 (Electronic) Linking ISSN: 11732563 NLM ISO Abbreviation: Clin Drug Investig Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42062754 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Pharmacokinetic Drug-Drug Interaction of Leritrelvir in Healthy Chinese Volunteers: A Single-Arm, Open-Label, Dual-Cohort Study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Peng+J%22">Peng J</searchLink>; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China.; Drug Clinical Trial Institution, Guangzhou Chest Hospital, Institute of Tuberculosis, Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Drug Clinical Trial Institution, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Du+XX%22">Du XX</searchLink>; Drug Clinical Trial Institution, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+HJ%22">Li HJ</searchLink>; Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Central South University, Changsha, China.; Guangdong Raynovent Biotechnology Co., Ltd., Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Qin+RZ%22">Qin RZ</searchLink>; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Chen+SH%22">Chen SH</searchLink>; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Cheng+Q%22">Cheng Q</searchLink>; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+XM%22">Li XM</searchLink>; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Huang+DX%22">Huang DX</searchLink>; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Duan+L%22">Duan L</searchLink>; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+MY%22">Li MY</searchLink>; Department of Cardiology, Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wu+WZ%22">Wu WZ</searchLink>; Department of Urology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Ye+LK%22">Ye LK</searchLink>; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+YY%22">Li YY</searchLink>; Guangdong Raynovent Biotechnology Co., Ltd., Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Xie+ZH%22">Xie ZH</searchLink>; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China. xzh0302@126.com.<br /><searchLink fieldCode="AU" term="%22Han+K%22">Han K</searchLink>; Phase I Clinical Trial Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 511447, Guangdong, China. cjy-ke@163.com.; Drug Clinical Trial Institution, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. cjy-ke@163.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229504817%22">Clinical drug investigation</searchLink> [Clin Drug Investig] 2026 Jun; Vol. 46 (6), pp. 609-618. <i>Date of Electronic Publication: </i>2026 May 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase I – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Adis%2C+Springer+International%22">Adis, Springer International </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>9504817 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1179-1918 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211732563%22">11732563 </searchLink><i>NLM ISO Abbreviation: </i>Clin Drug Investig <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42062754 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s40261-026-01556-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 609 Titles: – TitleFull: Pharmacokinetic Drug-Drug Interaction of Leritrelvir in Healthy Chinese Volunteers: A Single-Arm, Open-Label, Dual-Cohort Study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Peng J – PersonEntity: Name: NameFull: Chen J – PersonEntity: Name: NameFull: Du XX – PersonEntity: Name: NameFull: Li HJ – PersonEntity: Name: NameFull: Qin RZ – PersonEntity: Name: NameFull: Chen SH – PersonEntity: Name: NameFull: Liu X – PersonEntity: Name: NameFull: Cheng Q – PersonEntity: Name: NameFull: Li XM – PersonEntity: Name: NameFull: Huang DX – PersonEntity: Name: NameFull: Duan L – PersonEntity: Name: NameFull: Li MY – PersonEntity: Name: NameFull: Wu WZ – PersonEntity: Name: NameFull: Ye LK – PersonEntity: Name: NameFull: Li YY – PersonEntity: Name: NameFull: Xie ZH – PersonEntity: Name: NameFull: Han K IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2026 Jun Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1179-1918 Numbering: – Type: volume Value: 46 – Type: issue Value: 6 Titles: – TitleFull: Clinical drug investigation Type: main |
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