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Sennoside A alleviates HFD-induced MAFLD by protecting intestinal barrier function through TLR4/NF-κB and mitochondrial quality control.

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Title: Sennoside A alleviates HFD-induced MAFLD by protecting intestinal barrier function through TLR4/NF-κB and mitochondrial quality control.
Authors: Ma L; Department of Endocrinology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China. Electronic address: mali0177@126.com., Yuan C; Department of Cardiology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China., Cao X; Department of Geriatric Medicine, Shaanxi Provincial People's Hospital, Xi'an 710068, China; Diabetes Institute, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 201306, China. Electronic address: 374912045@qq.com., Sun Y; Department of Cardiology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China. Electronic address: ynsun2002@126.com.
Source: Pathology, research and practice [Pathol Res Pract] 2026 Jul; Vol. 283, pp. 156482. Date of Electronic Publication: 2026 Apr 23.
Publication Type: Journal Article
Journal Info: Publisher: Gustav Fischer Verlag Country of Publication: Germany NLM ID: 7806109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0631 (Electronic) Linking ISSN: 03440338 NLM ISO Abbreviation: Pathol Res Pract Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1618-0631
DOI:10.1016/j.prp.2026.156482