Unraveling the spatial landscape of dystrophinopathies: a transcriptomic approach to Becker and Duchenne muscular dystrophies.

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Title: Unraveling the spatial landscape of dystrophinopathies: a transcriptomic approach to Becker and Duchenne muscular dystrophies.
Authors: Heezen LG; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Mao Q; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Nicolau S; Center for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA., Rausell CN; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., van der Weerd J; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Kueckelhaus J; Microenvironment and Immunology Research Laboratory, Medical Center, Faculty of Medicine, Freiburg University, Freiburg, Germany.; Department of Neurosurgery, Medical Center, Faculty of Medicine, Erlangen University, Erlangen, Germany., Gokul Nath R; John Walton Muscular Dystrophy Research Centre, Newcastle University Translational and Clinical Research Institute, Newcastle Upon Tyne NHS Trust, Newcastle Upon Tyne, UK., Diaz-Manera J; John Walton Muscular Dystrophy Research Centre, Newcastle University Translational and Clinical Research Institute, Newcastle Upon Tyne NHS Trust, Newcastle Upon Tyne, UK.; Laboratori de Malalties Neuromusculars, Institu de recerca Hospital Sant Pau, Barcelona, Spain.; Centro de Investigación Biomédica en red de enfermedades raras (CIBERER), Madrid, Spain., Kan HE; Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.; Duchenne Center, The Netherlands., Niks EH; Duchenne Center, The Netherlands.; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands., van Putten M; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.; Duchenne Center, The Netherlands., Aartsma-Rus A; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.; Duchenne Center, The Netherlands., Flanigan KM; Center for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.; Department of Pediatrics, The Ohio State University, Columbus, OH, USA.; Department of Neurology, The Ohio State University, Columbus, OH, USA., Mahfouz A; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands., Spitali P; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.; Duchenne Center, The Netherlands.
Source: The Journal of pathology [J Pathol] 2026 Jul; Vol. 269 (3), pp. 363-380. Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1096-9896
DOI:10.1002/path.70067