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Interferon-alpha selectively signals mitochondrial pore opening to allow mitochondrial RNA release in systemic lupus erythematosus: pathophysiological implications.

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Title: Interferon-alpha selectively signals mitochondrial pore opening to allow mitochondrial RNA release in systemic lupus erythematosus: pathophysiological implications.
Authors: Huang CY; Institute of Cellular and System Medicine, National Health Research Institute, Zhunan, Taiwan, ROC.; Graduate Institute of Life Sciences, College of Biomedical Sciences, National Defense Medical University, Taipei, Taiwan, ROC., Wu DW; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Lin-Kou, Tao-Yuan, Taiwan, ROC., Hung LF; Institute of Cellular and System Medicine, National Health Research Institute, Zhunan, Taiwan, ROC., Wu CH; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Lin-Kou, Tao-Yuan, Taiwan, ROC., Luo SF; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Lin-Kou, Tao-Yuan, Taiwan, ROC., Ka SM; Graduate Institute of Aerospace and Undersea Medicine, Department of Medicine, National Defense Medical University, Taipei, Taiwan, ROC., Chen A; Department of Pathology, Hualien TZU CHI Medical Center, Hualien, Taiwan, ROC., Ho LJ; Institute of Cellular and System Medicine, National Health Research Institute, Zhunan, Taiwan, ROC. lingjunho@nhri.org.tw.; Graduate Institute of Life Sciences, College of Biomedical Sciences, National Defense Medical University, Taipei, Taiwan, ROC. lingjunho@nhri.org.tw., Lai JH; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Lin-Kou, Tao-Yuan, Taiwan, ROC. laiandho@gmail.com.; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan, ROC. laiandho@gmail.com.
Source: Cell communication and signaling : CCS [Cell Commun Signal] 2026 May 01; Vol. 24 (1). Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Interferon-alpha selectively signals mitochondrial pore opening to allow mitochondrial RNA release in systemic lupus erythematosus: pathophysiological implications.
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  Data: <searchLink fieldCode="AU" term="%22Huang+CY%22">Huang CY</searchLink>; Institute of Cellular and System Medicine, National Health Research Institute, Zhunan, Taiwan, ROC.; Graduate Institute of Life Sciences, College of Biomedical Sciences, National Defense Medical University, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Wu+DW%22">Wu DW</searchLink>; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Lin-Kou, Tao-Yuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Hung+LF%22">Hung LF</searchLink>; Institute of Cellular and System Medicine, National Health Research Institute, Zhunan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Wu+CH%22">Wu CH</searchLink>; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Lin-Kou, Tao-Yuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Luo+SF%22">Luo SF</searchLink>; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Lin-Kou, Tao-Yuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Ka+SM%22">Ka SM</searchLink>; Graduate Institute of Aerospace and Undersea Medicine, Department of Medicine, National Defense Medical University, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chen+A%22">Chen A</searchLink>; Department of Pathology, Hualien TZU CHI Medical Center, Hualien, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Ho+LJ%22">Ho LJ</searchLink>; Institute of Cellular and System Medicine, National Health Research Institute, Zhunan, Taiwan, ROC. lingjunho@nhri.org.tw.; Graduate Institute of Life Sciences, College of Biomedical Sciences, National Defense Medical University, Taipei, Taiwan, ROC. lingjunho@nhri.org.tw.<br /><searchLink fieldCode="AU" term="%22Lai+JH%22">Lai JH</searchLink>; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Lin-Kou, Tao-Yuan, Taiwan, ROC. laiandho@gmail.com.; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan, ROC. laiandho@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101170464%22">Cell communication and signaling : CCS</searchLink> [Cell Commun Signal] 2026 May 01; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 May 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101170464 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1478-811X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221478811X%22">1478811X </searchLink><i>NLM ISO Abbreviation: </i>Cell Commun Signal <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12964-026-02910-3
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        Text: English
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      – TitleFull: Interferon-alpha selectively signals mitochondrial pore opening to allow mitochondrial RNA release in systemic lupus erythematosus: pathophysiological implications.
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            – D: 01
              M: 05
              Text: 2026 May 01
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              Y: 2026
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