High affinity is insufficient for strong B cell activation by HIV broadly neutralising antibodies.

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Title: High affinity is insufficient for strong B cell activation by HIV broadly neutralising antibodies.
Authors: Rees-Spear C; Institute for Immunity and Transplantation, UCL, London, UK., Payne O; Institute for Immunity and Transplantation, UCL, London, UK., Touizer E; Institute for Immunity and Transplantation, UCL, London, UK., Kennedy A; Institute for Immunity and Transplantation, UCL, London, UK., Muir L; Institute for Immunity and Transplantation, UCL, London, UK., Thomas P; Institute for Immunity and Transplantation, UCL, London, UK., Thomas DeCruz A; London Centre for Nanotechnology, UCL, London, UK., McKendry RA; London Centre for Nanotechnology, UCL, London, UK., Swadling L; Institute for Immunity and Transplantation, UCL, London, UK., van Gils MJ; UMC, Amsterdam, the Netherlands., Voss JE; The Scripps Research Institute, La Jolla, CA, USA., McCoy LE; Institute for Immunity and Transplantation, UCL, London, UK. l.mccoy@ucl.ac.uk.
Source: NPJ vaccines [NPJ Vaccines] 2026 May 02; Vol. 11 (1). Date of Electronic Publication: 2026 May 02.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2059-0105
DOI:10.1038/s41541-026-01468-y