High affinity is insufficient for strong B cell activation by HIV broadly neutralising antibodies.

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Title: High affinity is insufficient for strong B cell activation by HIV broadly neutralising antibodies.
Authors: Rees-Spear C; Institute for Immunity and Transplantation, UCL, London, UK., Payne O; Institute for Immunity and Transplantation, UCL, London, UK., Touizer E; Institute for Immunity and Transplantation, UCL, London, UK., Kennedy A; Institute for Immunity and Transplantation, UCL, London, UK., Muir L; Institute for Immunity and Transplantation, UCL, London, UK., Thomas P; Institute for Immunity and Transplantation, UCL, London, UK., Thomas DeCruz A; London Centre for Nanotechnology, UCL, London, UK., McKendry RA; London Centre for Nanotechnology, UCL, London, UK., Swadling L; Institute for Immunity and Transplantation, UCL, London, UK., van Gils MJ; UMC, Amsterdam, the Netherlands., Voss JE; The Scripps Research Institute, La Jolla, CA, USA., McCoy LE; Institute for Immunity and Transplantation, UCL, London, UK. l.mccoy@ucl.ac.uk.
Source: NPJ vaccines [NPJ Vaccines] 2026 May 02; Vol. 11 (1). Date of Electronic Publication: 2026 May 02.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: High affinity is insufficient for strong B cell activation by HIV broadly neutralising antibodies.
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  Data: <searchLink fieldCode="AU" term="%22Rees-Spear+C%22">Rees-Spear C</searchLink>; Institute for Immunity and Transplantation, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Payne+O%22">Payne O</searchLink>; Institute for Immunity and Transplantation, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Touizer+E%22">Touizer E</searchLink>; Institute for Immunity and Transplantation, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Kennedy+A%22">Kennedy A</searchLink>; Institute for Immunity and Transplantation, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Muir+L%22">Muir L</searchLink>; Institute for Immunity and Transplantation, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Thomas+P%22">Thomas P</searchLink>; Institute for Immunity and Transplantation, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Thomas+DeCruz+A%22">Thomas DeCruz A</searchLink>; London Centre for Nanotechnology, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22McKendry+RA%22">McKendry RA</searchLink>; London Centre for Nanotechnology, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Swadling+L%22">Swadling L</searchLink>; Institute for Immunity and Transplantation, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22van+Gils+MJ%22">van Gils MJ</searchLink>; UMC, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Voss+JE%22">Voss JE</searchLink>; The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22McCoy+LE%22">McCoy LE</searchLink>; Institute for Immunity and Transplantation, UCL, London, UK. l.mccoy@ucl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101699863%22">NPJ vaccines</searchLink> [NPJ Vaccines] 2026 May 02; Vol. 11 (1). <i>Date of Electronic Publication: </i>2026 May 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature+in+partnership+with+the+Sealy+Center+for+Vaccine+Development%22">Springer Nature in partnership with the Sealy Center for Vaccine Development </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101699863 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-0105 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220590105%22">20590105 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Vaccines <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1038/s41541-026-01468-y
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              Text: 2026 May 02
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