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Integrated single-cell transcriptomics and in vivo investigation reveal the role of ANXA1 in intestinal barrier dysfunction during heat stroke by mediating neutrophil-monocyte interaction and regulating the TLR4/ERK/NF-κB pathway.

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Title: Integrated single-cell transcriptomics and in vivo investigation reveal the role of ANXA1 in intestinal barrier dysfunction during heat stroke by mediating neutrophil-monocyte interaction and regulating the TLR4/ERK/NF-κB pathway.
Authors: Li J; Department of Critical Care Medicine, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fujian Provincial Center for Critical Care Medicine, Fujian Provincial Key Laboratory of Critical Care Medicine, Fuzhou, 350001, China., Chen X; Department of Critical Care Medicine, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fujian Provincial Center for Critical Care Medicine, Fujian Provincial Key Laboratory of Critical Care Medicine, Fuzhou, 350001, China., Tong Z; Department of Critical Care Medicine, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fujian Provincial Center for Critical Care Medicine, Fujian Provincial Key Laboratory of Critical Care Medicine, Fuzhou, 350001, China., Jin Y; Department of Traditional Chinese Medicine, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China. Electronic address: jinyishun@fjsl.com.cn.
Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2026 Jul 09; Vol. 821, pp. 153873. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrated single-cell transcriptomics and in vivo investigation reveal the role of ANXA1 in intestinal barrier dysfunction during heat stroke by mediating neutrophil-monocyte interaction and regulating the TLR4/ERK/NF-κB pathway.
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  Data: <searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Critical Care Medicine, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fujian Provincial Center for Critical Care Medicine, Fujian Provincial Key Laboratory of Critical Care Medicine, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Department of Critical Care Medicine, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fujian Provincial Center for Critical Care Medicine, Fujian Provincial Key Laboratory of Critical Care Medicine, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Tong+Z%22">Tong Z</searchLink>; Department of Critical Care Medicine, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fujian Provincial Center for Critical Care Medicine, Fujian Provincial Key Laboratory of Critical Care Medicine, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Jin+Y%22">Jin Y</searchLink>; Department of Traditional Chinese Medicine, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China. Electronic address: jinyishun@fjsl.com.cn.
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  Data: <searchLink fieldCode="JN" term="%220372516%22">Biochemical and biophysical research communications</searchLink> [Biochem Biophys Res Commun] 2026 Jul 09; Vol. 821, pp. 153873. <i>Date of Electronic Publication: </i>2026 Apr 30.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372516 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2104 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220006291X%22">0006291X </searchLink><i>NLM ISO Abbreviation: </i>Biochem Biophys Res Commun <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bbrc.2026.153873
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      – TitleFull: Integrated single-cell transcriptomics and in vivo investigation reveal the role of ANXA1 in intestinal barrier dysfunction during heat stroke by mediating neutrophil-monocyte interaction and regulating the TLR4/ERK/NF-κB pathway.
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              Text: 2026 Jul 09
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