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Differential Modulation of JAK/STAT3 Signaling and BCL-2 Family Proteins by Tetracycline Analogues in Leukemia Models.

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Title: Differential Modulation of JAK/STAT3 Signaling and BCL-2 Family Proteins by Tetracycline Analogues in Leukemia Models.
Authors: Hassan ZM; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.; Experimental Cancer Medicine, Division of Biomolecular and Cellular Medicine (BCM), Department of Laboratory Medicine, Karolinska Institutet, 141 86 Huddinge, Sweden., Mamand DR; Department of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.; Breast Center, Karolinska Comprehensive Cancer Center, Karolinska University Hospital, 171 76 Stockholm, Sweden.; Biology Research Center, Research Center, University of Zakho, Zakho 42002, Duhok, Kurdistan Region, Iraq., El-Gawly HW; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt., El-Sherbeeny NA; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt., Mohammad HMF; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt., Elkherbetawy MK; Department of Pathology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt., Wiklander OPB; Department of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.; Breast Center, Karolinska Comprehensive Cancer Center, Karolinska University Hospital, 171 76 Stockholm, Sweden., Hassan M; Experimental Cancer Medicine, Division of Biomolecular and Cellular Medicine (BCM), Department of Laboratory Medicine, Karolinska Institutet, 141 86 Huddinge, Sweden.
Source: Pharmaceutics [Pharmaceutics] 2026 Mar 28; Vol. 18 (4). Date of Electronic Publication: 2026 Mar 28.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Differential Modulation of JAK/STAT3 Signaling and BCL-2 Family Proteins by Tetracycline Analogues in Leukemia Models.
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  Data: <searchLink fieldCode="AU" term="%22Hassan+ZM%22">Hassan ZM</searchLink>; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.; Experimental Cancer Medicine, Division of Biomolecular and Cellular Medicine (BCM), Department of Laboratory Medicine, Karolinska Institutet, 141 86 Huddinge, Sweden.<br /><searchLink fieldCode="AU" term="%22Mamand+DR%22">Mamand DR</searchLink>; Department of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.; Breast Center, Karolinska Comprehensive Cancer Center, Karolinska University Hospital, 171 76 Stockholm, Sweden.; Biology Research Center, Research Center, University of Zakho, Zakho 42002, Duhok, Kurdistan Region, Iraq.<br /><searchLink fieldCode="AU" term="%22El-Gawly+HW%22">El-Gawly HW</searchLink>; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Sherbeeny+NA%22">El-Sherbeeny NA</searchLink>; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.<br /><searchLink fieldCode="AU" term="%22Mohammad+HMF%22">Mohammad HMF</searchLink>; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.<br /><searchLink fieldCode="AU" term="%22Elkherbetawy+MK%22">Elkherbetawy MK</searchLink>; Department of Pathology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.<br /><searchLink fieldCode="AU" term="%22Wiklander+OPB%22">Wiklander OPB</searchLink>; Department of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.; Breast Center, Karolinska Comprehensive Cancer Center, Karolinska University Hospital, 171 76 Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Hassan+M%22">Hassan M</searchLink>; Experimental Cancer Medicine, Division of Biomolecular and Cellular Medicine (BCM), Department of Laboratory Medicine, Karolinska Institutet, 141 86 Huddinge, Sweden.
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  Data: <searchLink fieldCode="JN" term="%22101534003%22">Pharmaceutics</searchLink> [Pharmaceutics] 2026 Mar 28; Vol. 18 (4). <i>Date of Electronic Publication: </i>2026 Mar 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101534003 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1999-4923 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219994923%22">19994923 </searchLink><i>NLM ISO Abbreviation: </i>Pharmaceutics <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3390/pharmaceutics18040415
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        Text: English
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      – TitleFull: Differential Modulation of JAK/STAT3 Signaling and BCL-2 Family Proteins by Tetracycline Analogues in Leukemia Models.
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              Text: 2026 Mar 28
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