Single-cell landscape of melanoma reveals ETV5-driven C3 ID4+ tumor subpopulation with extracellular vesicle-associated immunosuppressive and pro-metastatic potential.

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Title: Single-cell landscape of melanoma reveals ETV5-driven C3 ID4+ tumor subpopulation with extracellular vesicle-associated immunosuppressive and pro-metastatic potential.
Authors: Li H; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Department of Facial Plastic and Reconstructive Surgery, Eye & ENT Hospital of Fudan University, Shanghai, China., Zheng X; School of Medicine, Shanghai Jiao Tong University, Shanghai, China., Gong Y; Department of Dermatology, Shanghai Minhang District Traditional Chinese Medicine Hospital, Shanghai, China., Xi M; Fudan University-Doctor Kong Joint Research Center for Sports Medicine and Health Footwear, Fudan University Institute of Sports Medicine, Jinqiao Laboratory, Shanghai, China., Sun H; Department of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, China., Ding Y; Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, China.; Key Laboratory of Dermatology, Anhui Medical University, Ministry of Education, Hefei, Anhui, China., Sun Q; Department of Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Source: Frontiers in immunology [Front Immunol] 2026 Apr 16; Vol. 17, pp. 1795778. Date of Electronic Publication: 2026 Apr 16 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1795778