Single-cell landscape of melanoma reveals ETV5-driven C3 ID4+ tumor subpopulation with extracellular vesicle-associated immunosuppressive and pro-metastatic potential.

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Title: Single-cell landscape of melanoma reveals ETV5-driven C3 ID4+ tumor subpopulation with extracellular vesicle-associated immunosuppressive and pro-metastatic potential.
Authors: Li H; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Department of Facial Plastic and Reconstructive Surgery, Eye & ENT Hospital of Fudan University, Shanghai, China., Zheng X; School of Medicine, Shanghai Jiao Tong University, Shanghai, China., Gong Y; Department of Dermatology, Shanghai Minhang District Traditional Chinese Medicine Hospital, Shanghai, China., Xi M; Fudan University-Doctor Kong Joint Research Center for Sports Medicine and Health Footwear, Fudan University Institute of Sports Medicine, Jinqiao Laboratory, Shanghai, China., Sun H; Department of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, China., Ding Y; Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, China.; Key Laboratory of Dermatology, Anhui Medical University, Ministry of Education, Hefei, Anhui, China., Sun Q; Department of Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Source: Frontiers in immunology [Front Immunol] 2026 Apr 16; Vol. 17, pp. 1795778. Date of Electronic Publication: 2026 Apr 16 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Single-cell landscape of melanoma reveals ETV5-driven C3 ID4<superscript>+</superscript> tumor subpopulation with extracellular vesicle-associated immunosuppressive and pro-metastatic potential.
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  Data: <searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Department of Facial Plastic and Reconstructive Surgery, Eye & ENT Hospital of Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zheng+X%22">Zheng X</searchLink>; School of Medicine, Shanghai Jiao Tong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Gong+Y%22">Gong Y</searchLink>; Department of Dermatology, Shanghai Minhang District Traditional Chinese Medicine Hospital, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Xi+M%22">Xi M</searchLink>; Fudan University-Doctor Kong Joint Research Center for Sports Medicine and Health Footwear, Fudan University Institute of Sports Medicine, Jinqiao Laboratory, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Sun+H%22">Sun H</searchLink>; Department of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.<br /><searchLink fieldCode="AU" term="%22Ding+Y%22">Ding Y</searchLink>; Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, China.; Key Laboratory of Dermatology, Anhui Medical University, Ministry of Education, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Sun+Q%22">Sun Q</searchLink>; Department of Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Apr 16; Vol. 17, pp. 1795778. <i>Date of Electronic Publication: </i>2026 Apr 16 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.3389/fimmu.2026.1795778
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        Text: English
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      – TitleFull: Single-cell landscape of melanoma reveals ETV5-driven C3 ID4+ tumor subpopulation with extracellular vesicle-associated immunosuppressive and pro-metastatic potential.
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            – D: 16
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              Text: 2026 Apr 16
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              Y: 2026
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