NH600001, an etomidate analogue, provides gastrointestinal endoscopy sedation/anesthesia and reduces adrenocortical depression: two randomized controlled trials.
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| Title: | NH600001, an etomidate analogue, provides gastrointestinal endoscopy sedation/anesthesia and reduces adrenocortical depression: two randomized controlled trials. |
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| Authors: | Zhou Y; Department of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha, China., Duan K; Department of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha, China., Luo S; Department of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha, China., Liu S; Department of Endocrinology, The Third Xiangya Hospital of Central South University, Changsha, China., Li Q; Department of Anesthesiology, Changsha Central Hospital, Changsha, China., Liu S; Department of Anesthesiology, Changsha Central Hospital, Changsha, China., Guo H; Department of Anesthesiology, The First People's Hospital of Changde, Changde, China., Jiang H; Department of Anesthesiology, Yueyang People's Hospital, Yueyang, China., Wang G; Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Wang H; Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Wang Z; Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China., Zhang X; Department of Anesthesiology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, The First People's Hospital of Lianyungang, Lianyungang, China., Sun C; Department of Anesthesiology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China., Wang Q; Department of Anesthesiology & Center for Brain Science, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Gao W; Department of Anesthesiology & Center for Brain Science, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Shangguan W; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China., Xia Z; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China., Luo A; Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Chen C; Department of Anesthesiology, Yichang Central People's Hospital, Yichang, China., Yang M; Department of Anesthesiology, Sichuan Academy of Medical Sciences-Sichuan Provincial People's Hospital (SAMSPH), Chengdu, China., Su W; Department of Anesthesiology, Sichuan Academy of Medical Sciences-Sichuan Provincial People's Hospital (SAMSPH), Chengdu, China., Zou X; Department of Anesthesiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China., Li Y; Department of Anesthesiology, The First Affiliated Hospital of Jinan University, Guangzhou, China., Wang H; Department of Anesthesiology, The First Affiliated Hospital of Jinan University, Guangzhou, China., Huang Y; Department of Anesthesiology, The Third Affiliated Hospital of Guangxi Medical University, Nanning Second People's Hospital, Nanning, Guangxi, China., Dai R; Department of Anesthesiology, The Second Xiangya Hospital of Central South University, Changsha, China., Zhao Q; Department of Anesthesiology, The Fourth Hospital of Changsha, Changsha, China., Jing S; Department of Anesthesiology, Jinan Central Hospital, Jinan, China., Zhang L; Department of Anesthesiology, The Second Hospital of Shanxi Medical University, Taiyuan, China., Yan W; Department of Anesthesiology, Gansu Provincial Hospital, Lanzhou, China., Qin X; Department of Anesthesiology, The Fifth Affiliated Hospital of Xinjiang Medical University, Xinjiang, China., Wang J; Department of Anesthesiology, Huaibei Miner General Hospital, Huaibei, China., Chen J; Department of Anesthesiology, Wuhan Central Hospital, Wuhan, China., Cao J; Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China., Zhang M; Department of Anesthesiology, Jiangxi Provincial People's Hospital, Nanchang, China., Yu S; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China., Ouyang W; Department of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha, China. ouyangwen139@126.com., Wang S; Department of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha, China. wsyxy3yy@csu.edu.cn. |
| Source: | Nature communications [Nat Commun] 2026 May 04; Vol. 17 (1). Date of Electronic Publication: 2026 May 04. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42082491 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: NH600001, an etomidate analogue, provides gastrointestinal endoscopy sedation/anesthesia and reduces adrenocortical depression: two randomized controlled trials. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Department of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Duan+K%22">Duan K</searchLink>; Department of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Luo+S%22">Luo S</searchLink>; Department of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Department of Endocrinology, The Third Xiangya Hospital of Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Department of Anesthesiology, Changsha Central Hospital, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Department of Anesthesiology, Changsha Central Hospital, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Guo+H%22">Guo H</searchLink>; Department of Anesthesiology, The First People's Hospital of Changde, Changde, China.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; Department of Anesthesiology, Yueyang People's Hospital, Yueyang, China.<br /><searchLink fieldCode="AU" term="%22Wang+G%22">Wang G</searchLink>; Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Anesthesiology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, The First People's Hospital of Lianyungang, Lianyungang, China.<br /><searchLink fieldCode="AU" term="%22Sun+C%22">Sun C</searchLink>; Department of Anesthesiology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Department of Anesthesiology & Center for Brain Science, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Gao+W%22">Gao W</searchLink>; Department of Anesthesiology & Center for Brain Science, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Shangguan+W%22">Shangguan W</searchLink>; Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.<br /><searchLink fieldCode="AU" term="%22Xia+Z%22">Xia Z</searchLink>; 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Department of Anesthesiology, The Second Hospital of Shanxi Medical University, Taiyuan, China.<br /><searchLink fieldCode="AU" term="%22Yan+W%22">Yan W</searchLink>; Department of Anesthesiology, Gansu Provincial Hospital, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Qin+X%22">Qin X</searchLink>; Department of Anesthesiology, The Fifth Affiliated Hospital of Xinjiang Medical University, Xinjiang, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Anesthesiology, Huaibei Miner General Hospital, Huaibei, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Anesthesiology, Wuhan Central Hospital, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Cao+J%22">Cao J</searchLink>; Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; Department of Anesthesiology, Jiangxi Provincial People's Hospital, Nanchang, China.<br /><searchLink fieldCode="AU" term="%22Yu+S%22">Yu S</searchLink>; Department of Anesthesiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.<br /><searchLink fieldCode="AU" term="%22Ouyang+W%22">Ouyang W</searchLink>; Department of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha, China. ouyangwen139@126.com.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Department of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha, China. wsyxy3yy@csu.edu.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 May 04; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 May 04. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. 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