Annexin A1 alleviates heatstroke by inhibiting RIPK3/MLKL-mediated necroptosis through an FPR2-dependent pathway in male mice.
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| Title: | Annexin A1 alleviates heatstroke by inhibiting RIPK3/MLKL-mediated necroptosis through an FPR2-dependent pathway in male mice. |
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| Authors: | Feng B; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Li H; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Pan XD; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China.; Department of Emergency Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China., Zhang WY; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Li XY; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Jiang YT; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Liu LF; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Bhandari S; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Luo J; Department of Pharmacy, Taizhou Women and Children's Hospital of Wenzhou Medical University, Taizhou, China., Weng HX; Department of Critical Care Medicine, The Third Affiliated Hospital of Wenzhou Medical University, Ruian, China., Chen J; Department of Emergency, The Third Affiliated Hospital of Wenzhou Medical University, Ruian, China., Ding YJ; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Chen T; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Jin HX; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Zhu XY; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Xin XM; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Gong YQ; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Jin SW; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China., Hao Y; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Paediatric Anaesthesiology, Ministry of Education, Wenzhou Medical University, Wenzhou, China.; Precision Anaesthesiology Key Laboratory of Zhejiang Province, Wenzhou Medical University, Wenzhou, China.; Wenzhou Key Laboratory of Precision General Practice and Health Management, Wenzhou, China. |
| Source: | British journal of pharmacology [Br J Pharmacol] 2026 Aug; Vol. 183 (16), pp. 4698-4714. Date of Electronic Publication: 2026 May 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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