NVX-CoV2372, monovalent mRNA and bivalent mRNA vaccines elicit broadly cross-reactive antibodies against emerging SARS-CoV-2 variants.

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Title: NVX-CoV2372, monovalent mRNA and bivalent mRNA vaccines elicit broadly cross-reactive antibodies against emerging SARS-CoV-2 variants.
Authors: Poh XY; Singapore Infectious Disease Clinical Research Network, Communicable Diseases Agency (CDA), Singapore, Singapore.; Clinical Trial Unit, NCID, Singapore, Singapore., Mah SYY; Emerging Infectious Diseases Programme, Duke-NUS Medical School, Singapore, Singapore., Yeoh AYY; Emerging Infectious Diseases Programme, Duke-NUS Medical School, Singapore, Singapore., Chavatte JM; National Public Health Laboratory, CDA, Singapore, Singapore., Lim DRX; National Public Health Laboratory, CDA, Singapore, Singapore., Tan CCY; National Public Health Laboratory, CDA, Singapore, Singapore., Tang HL; National Public Health Laboratory, CDA, Singapore, Singapore., Gandhi M; Singapore Clinical Research Institute, Consortium for Clinical Research and Innovation, Singapore, Singapore.; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore., Rahman N; Singapore Clinical Research Institute, Consortium for Clinical Research and Innovation, Singapore, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Rao S; Department of Infectious Diseases, National Centre for Infectious Diseases (NCID), Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore., Chia PY; Department of Infectious Diseases, National Centre for Infectious Diseases (NCID), Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Sadarangani SP; Department of Infectious Diseases, National Centre for Infectious Diseases (NCID), Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Clinical Advisor Office, CDA, Singapore, Singapore., Chin YQ; Clinical Trial Unit, NCID, Singapore, Singapore., Ng LFP; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; A*STAR Infectious Diseases Labs (A*STAR ID Labs), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Renia L; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; A*STAR Infectious Diseases Labs (A*STAR ID Labs), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lin RTP; National Public Health Laboratory, CDA, Singapore, Singapore., Lye DC; Department of Infectious Diseases, National Centre for Infectious Diseases (NCID), Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; CDA Research Group, CDA, Singapore, Singapore., Wang LF; Emerging Infectious Diseases Programme, Duke-NUS Medical School, Singapore, Singapore., Tan CW; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Young BE; Singapore Infectious Disease Clinical Research Network, Communicable Diseases Agency (CDA), Singapore, Singapore.; Clinical Trial Unit, NCID, Singapore, Singapore.; Department of Infectious Diseases, National Centre for Infectious Diseases (NCID), Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Source: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2026 Dec; Vol. 22 (1), pp. 2638022. Date of Electronic Publication: 2026 May 05.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2164-554X
DOI:10.1080/21645515.2026.2638022