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Exogenous 8-hydroxydeoxyguanosine prevents liver fibrosis through the regulation of Rac1-NADPH oxidase signaling in a metabolic dysfunction-associated steatohepatitis model.

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Title: Exogenous 8-hydroxydeoxyguanosine prevents liver fibrosis through the regulation of Rac1-NADPH oxidase signaling in a metabolic dysfunction-associated steatohepatitis model.
Authors: Lee Y; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Kim IS; Department of Microbiology, Gachon University College of Medicine, Incheon, Republic of Korea.; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea., Kim JW; College of Medicine, Gachon University, Incheon, Republic of Korea., Kim MK; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Chae YG; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Choi CS; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea., Kwon OS; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Kim YS; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Kim JH; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Chung DH; Department of Pathology, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Shin SK; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.
Source: Free radical research [Free Radic Res] 2026 May 11, pp. 1-12. Date of Electronic Publication: 2026 May 11.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9423872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1029-2470 (Electronic) Linking ISSN: 10292470 NLM ISO Abbreviation: Free Radic Res Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Lee+Y%22">Lee Y</searchLink>; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+IS%22">Kim IS</searchLink>; Department of Microbiology, Gachon University College of Medicine, Incheon, Republic of Korea.; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JW%22">Kim JW</searchLink>; College of Medicine, Gachon University, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+MK%22">Kim MK</searchLink>; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chae+YG%22">Chae YG</searchLink>; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+CS%22">Choi CS</searchLink>; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.; Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+OS%22">Kwon OS</searchLink>; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YS%22">Kim YS</searchLink>; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JH%22">Kim JH</searchLink>; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chung+DH%22">Chung DH</searchLink>; Department of Pathology, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+SK%22">Shin SK</searchLink>; Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%229423872%22">Free radical research</searchLink> [Free Radic Res] 2026 May 11, pp. 1-12. <i>Date of Electronic Publication: </i>2026 May 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Informa+Healthcare%22">Informa Healthcare </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9423872 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1029-2470 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210292470%22">10292470 </searchLink><i>NLM ISO Abbreviation: </i>Free Radic Res <i>Subsets: </i>MEDLINE
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              Text: 2026 May 11
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