The Kunduan Yimu decoction improves rheumatoid arthritis by targeting microRNA-155-5p to enhance autophagy and reduce inflammation.

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Title: The Kunduan Yimu decoction improves rheumatoid arthritis by targeting microRNA-155-5p to enhance autophagy and reduce inflammation.
Authors: Liu XB; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China., Zou FS; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China., Shi MF; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China., Ma XN; The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510006, China., Liu QP; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China., Lin CS; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China., Gao W; GuangDong Second Traditional Chinese Medicine Hospital, Guangzhou, China. Electronic address: gaowei972@163.com., Liu MY; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China; Chongqing Hospital, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, China. Electronic address: 343991629@qq.com., Xu Q; State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Guangdong Clinical Research Academy of Chinese Medicine, Guangzhou, China. Electronic address: fjksg@163.com.
Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2026 Jul; Vol. 156, pp. 158252. Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1618-095X
DOI:10.1016/j.phymed.2026.158252