Examining the risk of neurotoxicity in patients who receive unadjusted doses of oral beta-lactams in renal insufficiency: a retrospective cohort study.

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Title: Examining the risk of neurotoxicity in patients who receive unadjusted doses of oral beta-lactams in renal insufficiency: a retrospective cohort study.
Authors: Zlotnik N; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada., Lam PW; Sunnybrook Health Sciences Centre, Toronto, ON, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Centre for Quality Improvement and Patient Safety, University of Toronto, Toronto, ON, Canada., Lo J; Sunnybrook Health Sciences Centre, Toronto, ON, Canada., Palmay L; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.; Sunnybrook Health Sciences Centre, Toronto, ON, Canada., Leis JA; Sunnybrook Health Sciences Centre, Toronto, ON, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Centre for Quality Improvement and Patient Safety, University of Toronto, Toronto, ON, Canada., Daneman N; Sunnybrook Health Sciences Centre, Toronto, ON, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Elligsen M; Sunnybrook Health Sciences Centre, Toronto, ON, Canada. marion.elligsen@sunnybrook.ca.
Source: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2026 May 06; Vol. 82 (5). Date of Electronic Publication: 2026 May 06.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 1256165 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1041 (Electronic) Linking ISSN: 00316970 NLM ISO Abbreviation: Eur J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-1041
DOI:10.1007/s00228-026-04069-9