View in EDS

RMC-6272, a selective third-generation bi-steric mTORC1 inhibitor, improves cardiac function in pressure overload-induced cardiac hypertrophy.

Saved in:
Bibliographic Details
Title: RMC-6272, a selective third-generation bi-steric mTORC1 inhibitor, improves cardiac function in pressure overload-induced cardiac hypertrophy.
Authors: Rogge M; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), Heidelberg University Hospital, 69120, Heidelberg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120, Heidelberg, Germany., Fischer J; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), Heidelberg University Hospital, 69120, Heidelberg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120, Heidelberg, Germany., Jakobi T; Department of Internal Medicine and the Translational Cardiovascular Research Center, University of Arizona, College of Medicine, Phoenix, USA., Loewenthal Z; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), Heidelberg University Hospital, 69120, Heidelberg, Germany., Gupta P; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), Heidelberg University Hospital, 69120, Heidelberg, Germany., Jürgensen L; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), Heidelberg University Hospital, 69120, Heidelberg, Germany., Frey N; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), Heidelberg University Hospital, 69120, Heidelberg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120, Heidelberg, Germany., Sandmann C; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), Heidelberg University Hospital, 69120, Heidelberg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120, Heidelberg, Germany.; Department of Genetics, Harvard Medical School, Boston, MA, USA., Völkers M; Department of Internal Medicine III (Cardiology, Angiology, and Pneumology), Heidelberg University Hospital, 69120, Heidelberg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120, Heidelberg, Germany.
Source: Journal of molecular and cellular cardiology plus [J Mol Cell Cardiol Plus] 2026 Apr 16; Vol. 16, pp. 100847. Date of Electronic Publication: 2026 Apr 16 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 9918470779706676 Publication Model: eCollection Cited Medium: Internet ISSN: 2772-9761 (Electronic) Linking ISSN: 27729761 NLM ISO Abbreviation: J Mol Cell Cardiol Plus Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2772-9761
DOI:10.1016/j.jmccpl.2026.100847