Interface Architecture of a VHL-PROTAC Complex with and without Cullin-2.
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| Title: | Interface Architecture of a VHL-PROTAC Complex with and without Cullin-2. |
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| Authors: | Whitford EN; School of Chemistry & Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.; Native MS Guided Structural Biology Center, Georgia Institute of Technology, Atlanta, Georgia 30332, United States., Gilbert JD; Native MS Guided Structural Biology Center, The Ohio State University, Columbus, Ohio 43210, United States., Kostelic MM; Native MS Guided Structural Biology Center, The Ohio State University, Columbus, Ohio 43210, United States.; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States., Ehlinger AC; Target Enabling Technologies, AbbVie, 1 N. Waukegan Rd, North Chicago, Illinois 60064, United States., Thibaudeau TA; Target Enabling Technologies, AbbVie, 1 N. Waukegan Rd, North Chicago, Illinois 60064, United States., McLoughlin SM; Technology and Therapeutic Platforms, AbbVie, 1 N. Waukegan Rd, North Chicago, Illinois 60064, United States., Wysocki VH; School of Chemistry & Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.; Native MS Guided Structural Biology Center, Georgia Institute of Technology, Atlanta, Georgia 30332, United States. |
| Source: | Journal of the American Chemical Society [J Am Chem Soc] 2026 May 20; Vol. 148 (19), pp. 19730-19737. Date of Electronic Publication: 2026 May 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42089481 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Interface Architecture of a VHL-PROTAC Complex with and without Cullin-2. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Whitford+EN%22">Whitford EN</searchLink>; School of Chemistry & Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.; Native MS Guided Structural Biology Center, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.<br /><searchLink fieldCode="AU" term="%22Gilbert+JD%22">Gilbert JD</searchLink>; Native MS Guided Structural Biology Center, The Ohio State University, Columbus, Ohio 43210, United States.<br /><searchLink fieldCode="AU" term="%22Kostelic+MM%22">Kostelic MM</searchLink>; Native MS Guided Structural Biology Center, The Ohio State University, Columbus, Ohio 43210, United States.; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.<br /><searchLink fieldCode="AU" term="%22Ehlinger+AC%22">Ehlinger AC</searchLink>; Target Enabling Technologies, AbbVie, 1 N. Waukegan Rd, North Chicago, Illinois 60064, United States.<br /><searchLink fieldCode="AU" term="%22Thibaudeau+TA%22">Thibaudeau TA</searchLink>; Target Enabling Technologies, AbbVie, 1 N. Waukegan Rd, North Chicago, Illinois 60064, United States.<br /><searchLink fieldCode="AU" term="%22McLoughlin+SM%22">McLoughlin SM</searchLink>; Technology and Therapeutic Platforms, AbbVie, 1 N. Waukegan Rd, North Chicago, Illinois 60064, United States.<br /><searchLink fieldCode="AU" term="%22Wysocki+VH%22">Wysocki VH</searchLink>; School of Chemistry & Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.; Native MS Guided Structural Biology Center, Georgia Institute of Technology, Atlanta, Georgia 30332, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227503056%22">Journal of the American Chemical Society</searchLink> [J Am Chem Soc] 2026 May 20; Vol. 148 (19), pp. 19730-19737. <i>Date of Electronic Publication: </i>2026 May 06. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7503056 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-5126 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200027863%22">00027863 </searchLink><i>NLM ISO Abbreviation: </i>J Am Chem Soc <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42089481 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/jacs.6c01509 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 19730 Titles: – TitleFull: Interface Architecture of a VHL-PROTAC Complex with and without Cullin-2. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Whitford EN – PersonEntity: Name: NameFull: Gilbert JD – PersonEntity: Name: NameFull: Kostelic MM – PersonEntity: Name: NameFull: Ehlinger AC – PersonEntity: Name: NameFull: Thibaudeau TA – PersonEntity: Name: NameFull: McLoughlin SM – PersonEntity: Name: NameFull: Wysocki VH IsPartOfRelationships: – BibEntity: Dates: – D: 20 M: 05 Text: 2026 May 20 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1520-5126 Numbering: – Type: volume Value: 148 – Type: issue Value: 19 Titles: – TitleFull: Journal of the American Chemical Society Type: main |
| ResultId | 1 |
