Comprehensive Profiling of T- and B-Cell Receptor Repertoires Demonstrates Impaired Developmental and Activation of Adaptive Immunity in DOCK8 Deficiency.
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| Title: | Comprehensive Profiling of T- and B-Cell Receptor Repertoires Demonstrates Impaired Developmental and Activation of Adaptive Immunity in DOCK8 Deficiency. |
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| Authors: | Beit-Halevi T; Pediatric Department A and Immunology Service, Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel.; School of Medicine, Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel., Broides A; Pediatric Immunology Clinic, Joyce & Irving Goldman Medical School, Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel., Lev A; Pediatric Department A and Immunology Service, Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel., Simon AJ; Hemato-Immunology Unit, Hematology Lab, Sheba Cancer Research Center, Sheba Medical Center, Tel Hashomer, Israel., Nahum A; Pediatrics Department A, Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel., Somech R; Pediatric Department A and Immunology Service, Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel.; School of Medicine, Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel., Lee YN; Pediatric Department A and Immunology Service, Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel. yuneeya4u@gmail.com.; School of Medicine, Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel. yuneeya4u@gmail.com.; Pediatric Department A and the Immunology Service, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, 52621, Israel. yuneeya4u@gmail.com. |
| Source: | Journal of clinical immunology [J Clin Immunol] 2026 May 06; Vol. 46 (1). Date of Electronic Publication: 2026 May 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Netherlands NLM ID: 8102137 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2592 (Electronic) Linking ISSN: 02719142 NLM ISO Abbreviation: J Clin Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1573-2592 |
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| DOI: | 10.1007/s10875-026-02031-z |
