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A 2-year randomized trial of pitavastatin calcium vs placebo to treat combined dyslipidemia in adolescents with overweight and obesity.

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Title: A 2-year randomized trial of pitavastatin calcium vs placebo to treat combined dyslipidemia in adolescents with overweight and obesity.
Authors: McCrindle BW; The Hospital for Sick Children, University of Toronto, Toronto, Canada (McCrindle). Electronic address: brian.mccrindle@sickkids.ca., Arslanian S; University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA (Arslanian). Electronic address: silva.arslanian@chp.edu., Mietus-Snyder M; Children's National Hospital, George Washington University School of Medicine and Health Sciences, Washington, DC, USA (Mietus-Snyder). Electronic address: mmsnyder@childrensnational.org., Urbina EM; Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA (Urbina and Shah). Electronic address: elaine.urbina@cchmc.org., Ware AL; Primary Children's Hospital, University of Utah, Salt Lake City, UT, USA (Ware). Electronic address: adam.ware@hsc.utah.edu., Teng JE; Carelon Research, Newton, MA, USA (Teng, Trachtenberg, Sharma, and Kazlova). Electronic address: jessica.teng@carelon.com., Trachtenberg F; Carelon Research, Newton, MA, USA (Teng, Trachtenberg, Sharma, and Kazlova). Electronic address: felicia.trachtenberg@carelon.com., Russell MW; C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, MI, USA (Russell). Electronic address: mruss@med.umich.edu., Shah AS; Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA (Urbina and Shah). Electronic address: amy.shah@cchmc.org., Cartoski M; Nemours / Alfred I. DuPont Hospital for Children, Wilmington, DE, USA (Cartoski). Electronic address: mark.cartoski@nemours.org., Brothers JA; Children's Hospital of Philadelphia, University of Pennsylvania, PA, USA (Brothers). Electronic address: brothersj@chop.edu., Giovanni CS; Medical University of South Carolina, Charleston, SC, USA (Giovanni). Electronic address: sangiova@musc.edu., Zachariah JP; Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA (Zachariah and Pena). Electronic address: justin.zachariah@bcm.edu., Pena S; Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA (Zachariah and Pena). Electronic address: sypena@texaschildrens.org., Mahle WT; Children's Health Care of Atlanta, Emory University, Atlanta, GA, USA (Mahle). Electronic address: mahlew@kidsheart.org., Peterson AL; University of Wisconsin School of Medicine and Public Health, Madison, WI, USA (Peterson). Electronic address: apeterson@pediatrics.wisc.edu., Magge SN; Johns Hopkins University School of Medicine, Baltimore, MD, USA (Magge). Electronic address: smagge3@jhmi.edu., Raghuveer G; Children's Mercy Hospital, Kansas City, MO, USA (Raghuveer). Electronic address: graghuveer@cmh.edu., Sharma B; Carelon Research, Newton, MA, USA (Teng, Trachtenberg, Sharma, and Kazlova). Electronic address: binu.sharma@carelon.com., Kazlova V; Carelon Research, Newton, MA, USA (Teng, Trachtenberg, Sharma, and Kazlova). Electronic address: valiantsina.kazlova@carelon.com., Sponseller CA; Kowa Pharmaceuticals America, Montgomery, AL, USA (Sponseller). Electronic address: csponseller@kowapharma.com., Freemon D; National Heart, Lung and Blood Institute-NIH, Bethesda, MD, USA (Freemon and Stylianou). Electronic address: dandrea.freemon@nih.gov., Stylianou M; National Heart, Lung and Blood Institute-NIH, Bethesda, MD, USA (Freemon and Stylianou). Electronic address: stylianm@nhlbi.nih.gov., de Ferranti SD; Boston Children's Hospital, Harvard Medical School, Boston, MA, USA (de Ferranti). Electronic address: sarah.deferranti@cardio.chboston.org.
Corporate Authors: Pediatric Heart Network Investigators
Source: Journal of clinical lipidology [J Clin Lipidol] 2026 Jun; Vol. 20 (6), pp. 1212-1235. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101300157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-2874 (Print) Linking ISSN: 18764789 NLM ISO Abbreviation: J Clin Lipidol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
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DbLabel: MEDLINE Ultimate
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AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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Items – Name: Title
  Label: Title
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  Data: A 2-year randomized trial of pitavastatin calcium vs placebo to treat combined dyslipidemia in adolescents with overweight and obesity.
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  Data: <searchLink fieldCode="AU" term="%22McCrindle+BW%22">McCrindle BW</searchLink>; The Hospital for Sick Children, University of Toronto, Toronto, Canada (McCrindle). Electronic address: brian.mccrindle@sickkids.ca.<br /><searchLink fieldCode="AU" term="%22Arslanian+S%22">Arslanian S</searchLink>; University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA (Arslanian). Electronic address: silva.arslanian@chp.edu.<br /><searchLink fieldCode="AU" term="%22Mietus-Snyder+M%22">Mietus-Snyder M</searchLink>; Children's National Hospital, George Washington University School of Medicine and Health Sciences, Washington, DC, USA (Mietus-Snyder). Electronic address: mmsnyder@childrensnational.org.<br /><searchLink fieldCode="AU" term="%22Urbina+EM%22">Urbina EM</searchLink>; Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA (Urbina and Shah). Electronic address: elaine.urbina@cchmc.org.<br /><searchLink fieldCode="AU" term="%22Ware+AL%22">Ware AL</searchLink>; Primary Children's Hospital, University of Utah, Salt Lake City, UT, USA (Ware). Electronic address: adam.ware@hsc.utah.edu.<br /><searchLink fieldCode="AU" term="%22Teng+JE%22">Teng JE</searchLink>; Carelon Research, Newton, MA, USA (Teng, Trachtenberg, Sharma, and Kazlova). Electronic address: jessica.teng@carelon.com.<br /><searchLink fieldCode="AU" term="%22Trachtenberg+F%22">Trachtenberg F</searchLink>; Carelon Research, Newton, MA, USA (Teng, Trachtenberg, Sharma, and Kazlova). Electronic address: felicia.trachtenberg@carelon.com.<br /><searchLink fieldCode="AU" term="%22Russell+MW%22">Russell MW</searchLink>; C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, MI, USA (Russell). Electronic address: mruss@med.umich.edu.<br /><searchLink fieldCode="AU" term="%22Shah+AS%22">Shah AS</searchLink>; Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA (Urbina and Shah). Electronic address: amy.shah@cchmc.org.<br /><searchLink fieldCode="AU" term="%22Cartoski+M%22">Cartoski M</searchLink>; Nemours / Alfred I. DuPont Hospital for Children, Wilmington, DE, USA (Cartoski). Electronic address: mark.cartoski@nemours.org.<br /><searchLink fieldCode="AU" term="%22Brothers+JA%22">Brothers JA</searchLink>; Children's Hospital of Philadelphia, University of Pennsylvania, PA, USA (Brothers). Electronic address: brothersj@chop.edu.<br /><searchLink fieldCode="AU" term="%22Giovanni+CS%22">Giovanni CS</searchLink>; Medical University of South Carolina, Charleston, SC, USA (Giovanni). Electronic address: sangiova@musc.edu.<br /><searchLink fieldCode="AU" term="%22Zachariah+JP%22">Zachariah JP</searchLink>; Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA (Zachariah and Pena). Electronic address: justin.zachariah@bcm.edu.<br /><searchLink fieldCode="AU" term="%22Pena+S%22">Pena S</searchLink>; Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA (Zachariah and Pena). Electronic address: sypena@texaschildrens.org.<br /><searchLink fieldCode="AU" term="%22Mahle+WT%22">Mahle WT</searchLink>; Children's Health Care of Atlanta, Emory University, Atlanta, GA, USA (Mahle). Electronic address: mahlew@kidsheart.org.<br /><searchLink fieldCode="AU" term="%22Peterson+AL%22">Peterson AL</searchLink>; University of Wisconsin School of Medicine and Public Health, Madison, WI, USA (Peterson). Electronic address: apeterson@pediatrics.wisc.edu.<br /><searchLink fieldCode="AU" term="%22Magge+SN%22">Magge SN</searchLink>; Johns Hopkins University School of Medicine, Baltimore, MD, USA (Magge). Electronic address: smagge3@jhmi.edu.<br /><searchLink fieldCode="AU" term="%22Raghuveer+G%22">Raghuveer G</searchLink>; Children's Mercy Hospital, Kansas City, MO, USA (Raghuveer). Electronic address: graghuveer@cmh.edu.<br /><searchLink fieldCode="AU" term="%22Sharma+B%22">Sharma B</searchLink>; Carelon Research, Newton, MA, USA (Teng, Trachtenberg, Sharma, and Kazlova). Electronic address: binu.sharma@carelon.com.<br /><searchLink fieldCode="AU" term="%22Kazlova+V%22">Kazlova V</searchLink>; Carelon Research, Newton, MA, USA (Teng, Trachtenberg, Sharma, and Kazlova). Electronic address: valiantsina.kazlova@carelon.com.<br /><searchLink fieldCode="AU" term="%22Sponseller+CA%22">Sponseller CA</searchLink>; Kowa Pharmaceuticals America, Montgomery, AL, USA (Sponseller). Electronic address: csponseller@kowapharma.com.<br /><searchLink fieldCode="AU" term="%22Freemon+D%22">Freemon D</searchLink>; National Heart, Lung and Blood Institute-NIH, Bethesda, MD, USA (Freemon and Stylianou). Electronic address: dandrea.freemon@nih.gov.<br /><searchLink fieldCode="AU" term="%22Stylianou+M%22">Stylianou M</searchLink>; National Heart, Lung and Blood Institute-NIH, Bethesda, MD, USA (Freemon and Stylianou). Electronic address: stylianm@nhlbi.nih.gov.<br /><searchLink fieldCode="AU" term="%22de+Ferranti+SD%22">de Ferranti SD</searchLink>; Boston Children's Hospital, Harvard Medical School, Boston, MA, USA (de Ferranti). Electronic address: sarah.deferranti@cardio.chboston.org.
– Name: AuthorCorporate
  Label: Corporate Authors
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  Data: <searchLink fieldCode="CA" term="%22Pediatric+Heart+Network+Investigators%22">Pediatric Heart Network Investigators</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101300157%22">Journal of clinical lipidology</searchLink> [J Clin Lipidol] 2026 Jun; Vol. 20 (6), pp. 1212-1235. <i>Date of Electronic Publication: </i>2026 Apr 20.
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  Data: Journal Article; Randomized Controlled Trial
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101300157 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1933-2874 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218764789%22">18764789 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Lipidol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jacl.2026.04.007
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