Single-cell insights into maladaptive endothelial plasticity and therapeutic targets in diabetic vascular complications.

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Title: Single-cell insights into maladaptive endothelial plasticity and therapeutic targets in diabetic vascular complications.
Authors: Alnuaimi NS; Department of Biological Sciences, College of Medicine and Health Sciences, Khalifa University, Abu Dhabi, UAE.; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE., Lößlein L; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE., Mousa M; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.; Department of Public Health and Epidemiology, College of Medicine and Health Sciences, Khalifa University of Science and Technology, Abu Dhabi, UAE., Khader TA; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE., Alkhaaldi A; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.; Department of Biomedical Engineering, College of Medicine and Health Sciences, Khalifa University of Science and Technology, Abu Dhabi, UAE., Azzam SK; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE., Van Craenenbroeck AH; Department of Microbiology, Immunology and Transplantation, Nephrology and Renal Transplantation Research Group, KU Leuven, Leuven,, Belgium.; Department of Nephrology, University Hospitals UZ Leuven, Leuven, , Belgium., Ashraf SS; Department of Biological Sciences, College of Medicine and Health Sciences, Khalifa University, Abu Dhabi, UAE.; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE., Carmeliet P; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), VIB Center for Cancer Biology, KU Leuven, VIB, Leuven, , Belgium., Alsafar H; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE. habiba.alsafar@ku.ac.ae.; Department of Biomedical Engineering, College of Medicine and Health Sciences, Khalifa University of Science and Technology, Abu Dhabi, UAE. habiba.alsafar@ku.ac.ae.
Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2026 May 06; Vol. 25 (1). Date of Electronic Publication: 2026 May 06.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840 (Electronic) Linking ISSN: 14752840 NLM ISO Abbreviation: Cardiovasc Diabetol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1475-2840
DOI:10.1186/s12933-026-03187-z