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Single-cell insights into maladaptive endothelial plasticity and therapeutic targets in diabetic vascular complications.

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Title: Single-cell insights into maladaptive endothelial plasticity and therapeutic targets in diabetic vascular complications.
Authors: Alnuaimi NS; Department of Biological Sciences, College of Medicine and Health Sciences, Khalifa University, Abu Dhabi, UAE.; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE., Lößlein L; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE., Mousa M; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.; Department of Public Health and Epidemiology, College of Medicine and Health Sciences, Khalifa University of Science and Technology, Abu Dhabi, UAE., Khader TA; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE., Alkhaaldi A; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.; Department of Biomedical Engineering, College of Medicine and Health Sciences, Khalifa University of Science and Technology, Abu Dhabi, UAE., Azzam SK; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE., Van Craenenbroeck AH; Department of Microbiology, Immunology and Transplantation, Nephrology and Renal Transplantation Research Group, KU Leuven, Leuven,, Belgium.; Department of Nephrology, University Hospitals UZ Leuven, Leuven, , Belgium., Ashraf SS; Department of Biological Sciences, College of Medicine and Health Sciences, Khalifa University, Abu Dhabi, UAE.; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE., Carmeliet P; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), VIB Center for Cancer Biology, KU Leuven, VIB, Leuven, , Belgium., Alsafar H; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE. habiba.alsafar@ku.ac.ae.; Department of Biomedical Engineering, College of Medicine and Health Sciences, Khalifa University of Science and Technology, Abu Dhabi, UAE. habiba.alsafar@ku.ac.ae.
Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2026 May 06; Vol. 25 (1). Date of Electronic Publication: 2026 May 06.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840 (Electronic) Linking ISSN: 14752840 NLM ISO Abbreviation: Cardiovasc Diabetol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell insights into maladaptive endothelial plasticity and therapeutic targets in diabetic vascular complications.
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  Data: <searchLink fieldCode="AU" term="%22Alnuaimi+NS%22">Alnuaimi NS</searchLink>; Department of Biological Sciences, College of Medicine and Health Sciences, Khalifa University, Abu Dhabi, UAE.; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.<br /><searchLink fieldCode="AU" term="%22Lößlein+L%22">Lößlein L</searchLink>; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.<br /><searchLink fieldCode="AU" term="%22Mousa+M%22">Mousa M</searchLink>; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.; Department of Public Health and Epidemiology, College of Medicine and Health Sciences, Khalifa University of Science and Technology, Abu Dhabi, UAE.<br /><searchLink fieldCode="AU" term="%22Khader+TA%22">Khader TA</searchLink>; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.<br /><searchLink fieldCode="AU" term="%22Alkhaaldi+A%22">Alkhaaldi A</searchLink>; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.; Department of Biomedical Engineering, College of Medicine and Health Sciences, Khalifa University of Science and Technology, Abu Dhabi, UAE.<br /><searchLink fieldCode="AU" term="%22Azzam+SK%22">Azzam SK</searchLink>; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.<br /><searchLink fieldCode="AU" term="%22Van+Craenenbroeck+AH%22">Van Craenenbroeck AH</searchLink>; Department of Microbiology, Immunology and Transplantation, Nephrology and Renal Transplantation Research Group, KU Leuven, Leuven,, Belgium.; Department of Nephrology, University Hospitals UZ Leuven, Leuven, , Belgium.<br /><searchLink fieldCode="AU" term="%22Ashraf+SS%22">Ashraf SS</searchLink>; Department of Biological Sciences, College of Medicine and Health Sciences, Khalifa University, Abu Dhabi, UAE.; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.<br /><searchLink fieldCode="AU" term="%22Carmeliet+P%22">Carmeliet P</searchLink>; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE.; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), VIB Center for Cancer Biology, KU Leuven, VIB, Leuven, , Belgium.<br /><searchLink fieldCode="AU" term="%22Alsafar+H%22">Alsafar H</searchLink>; Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, UAE. habiba.alsafar@ku.ac.ae.; Department of Biomedical Engineering, College of Medicine and Health Sciences, Khalifa University of Science and Technology, Abu Dhabi, UAE. habiba.alsafar@ku.ac.ae.
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  Data: <searchLink fieldCode="JN" term="%22101147637%22">Cardiovascular diabetology</searchLink> [Cardiovasc Diabetol] 2026 May 06; Vol. 25 (1). <i>Date of Electronic Publication: </i>2026 May 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101147637 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1475-2840 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214752840%22">14752840 </searchLink><i>NLM ISO Abbreviation: </i>Cardiovasc Diabetol <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12933-026-03187-z
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      – Code: eng
        Text: English
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          Dates:
            – D: 06
              M: 05
              Text: 2026 May 06
              Type: published
              Y: 2026
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              Value: 25
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            – TitleFull: Cardiovascular diabetology
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