Enhancing validation of case-control omics signatures through "minimalist" single-subject analysis (N-of-1 trials): proof of concept in sepsis.
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| Title: | Enhancing validation of case-control omics signatures through "minimalist" single-subject analysis (N-of-1 trials): proof of concept in sepsis. |
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| Authors: | Wilson LS; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States., Pouladi N; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States., Nelson RF; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States., Middleton EA; Molecular Medicine Program, University of Utah, Salt Lake City, UT 84112, United States.; Department of Internal Medicine, University of Utah, Salt Lake City, UT 84112, United States.; Division of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, UT 84112, United States., Tolley ND; Molecular Medicine Program, University of Utah, Salt Lake City, UT 84112, United States., Shabanian M; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States., Kenost C; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States., Campbell RA; Molecular Medicine Program, University of Utah, Salt Lake City, UT 84112, United States.; Department of Internal Medicine, University of Utah, Salt Lake City, UT 84112, United States.; Division of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, UT 84112, United States.; Department of Pathology, University of Utah, Salt Lake City, UT 84112, United States.; Department of Emergency Medicine, Washington University, Saint Louis, MO 63110, United States., Rondina MT; Department of Internal Medicine, University of Utah, Salt Lake City, UT 84112, United States.; Division of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, UT 84112, United States.; Department of Pathology, University of Utah, Salt Lake City, UT 84112, United States.; Geriatric Research, Education, and Clinical Center (GRECC), G.E. Wahlen VAMC, Salt Lake City, UT 84148, United States., Lussier YA; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, United States.; Center for Genomic Medicine, University of Utah, Salt Lake City, UT 84112, United States. |
| Source: | Journal of the American Medical Informatics Association : JAMIA [J Am Med Inform Assoc] 2026 Jul 01; Vol. 33 (7), pp. 1293-1303. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 9430800 Publication Model: Print Cited Medium: Internet ISSN: 1527-974X (Electronic) Linking ISSN: 10675027 NLM ISO Abbreviation: J Am Med Inform Assoc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42093161 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Enhancing validation of case-control omics signatures through "minimalist" single-subject analysis (N-of-1 trials): proof of concept in sepsis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wilson+LS%22">Wilson LS</searchLink>; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States.<br /><searchLink fieldCode="AU" term="%22Pouladi+N%22">Pouladi N</searchLink>; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States.<br /><searchLink fieldCode="AU" term="%22Nelson+RF%22">Nelson RF</searchLink>; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States.<br /><searchLink fieldCode="AU" term="%22Middleton+EA%22">Middleton EA</searchLink>; Molecular Medicine Program, University of Utah, Salt Lake City, UT 84112, United States.; Department of Internal Medicine, University of Utah, Salt Lake City, UT 84112, United States.; Division of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, UT 84112, United States.<br /><searchLink fieldCode="AU" term="%22Tolley+ND%22">Tolley ND</searchLink>; Molecular Medicine Program, University of Utah, Salt Lake City, UT 84112, United States.<br /><searchLink fieldCode="AU" term="%22Shabanian+M%22">Shabanian M</searchLink>; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States.<br /><searchLink fieldCode="AU" term="%22Kenost+C%22">Kenost C</searchLink>; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States.<br /><searchLink fieldCode="AU" term="%22Campbell+RA%22">Campbell RA</searchLink>; Molecular Medicine Program, University of Utah, Salt Lake City, UT 84112, United States.; Department of Internal Medicine, University of Utah, Salt Lake City, UT 84112, United States.; Division of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, UT 84112, United States.; Department of Pathology, University of Utah, Salt Lake City, UT 84112, United States.; Department of Emergency Medicine, Washington University, Saint Louis, MO 63110, United States.<br /><searchLink fieldCode="AU" term="%22Rondina+MT%22">Rondina MT</searchLink>; Department of Internal Medicine, University of Utah, Salt Lake City, UT 84112, United States.; Division of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, UT 84112, United States.; Department of Pathology, University of Utah, Salt Lake City, UT 84112, United States.; Geriatric Research, Education, and Clinical Center (GRECC), G.E. Wahlen VAMC, Salt Lake City, UT 84148, United States.<br /><searchLink fieldCode="AU" term="%22Lussier+YA%22">Lussier YA</searchLink>; Department of Biomedical Informatics, University of Utah, Salt Lake City, UT 84108, United States.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, United States.; Center for Genomic Medicine, University of Utah, Salt Lake City, UT 84112, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229430800%22">Journal of the American Medical Informatics Association : JAMIA</searchLink> [J Am Med Inform Assoc] 2026 Jul 01; Vol. 33 (7), pp. 1293-1303. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9430800 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1527-974X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210675027%22">10675027 </searchLink><i>NLM ISO Abbreviation: </i>J Am Med Inform Assoc <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42093161 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1093/jamia/ocag061 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1293 Titles: – TitleFull: Enhancing validation of case-control omics signatures through "minimalist" single-subject analysis (N-of-1 trials): proof of concept in sepsis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wilson LS – PersonEntity: Name: NameFull: Pouladi N – PersonEntity: Name: NameFull: Nelson RF – PersonEntity: Name: NameFull: Middleton EA – PersonEntity: Name: NameFull: Tolley ND – PersonEntity: Name: NameFull: Shabanian M – PersonEntity: Name: NameFull: Kenost C – PersonEntity: Name: NameFull: Campbell RA – PersonEntity: Name: NameFull: Rondina MT – PersonEntity: Name: NameFull: Lussier YA IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2026 Jul 01 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1527-974X Numbering: – Type: volume Value: 33 – Type: issue Value: 7 Titles: – TitleFull: Journal of the American Medical Informatics Association : JAMIA Type: main |
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