Constitutive and inducible fibrosis explain immune variation among threespine stickleback populations.

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Title: Constitutive and inducible fibrosis explain immune variation among threespine stickleback populations.
Authors: Choi ES; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.; These authors contributed equally to this work.; Lead contact., Flanagan BA; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.; These authors contributed equally to this work., Alexander H; Bamfield Marine Sciences Centre, Bamfield, British Columbia, Canada, V0R 1B0., Berini J; Department of Biology, Carleton College, Northfield, Minnesota, USA., Yeung A; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA., Wolf CJ; Department of Integrative Biology, University of Wisconsin-Madison, Madison, Wisconsin, USA., Watts V; Bamfield Marine Sciences Centre, Bamfield, British Columbia, Canada, V0R 1B0.; University of Victoria, Victoria, British Columbia, Canada., Vaziri G; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.; Current address: University of Minnesota., Vargas N; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA., Szajada C; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA., Steffen P; Department of Biology, Carleton College, Northfield, Minnesota, USA., Srinivas I; Department of Pathobiological Science, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA., Shahid M; Department of Biology, Carleton College, Northfield, Minnesota, USA., Santacruz A; Stowers Institute for Medical Research, Kansas City, MO, USA.; Current address: Institute for Integrative Cell Biology and Physiology, University of Münster, Münster, Germany., Rochon K; Bamfield Marine Sciences Centre, Bamfield, British Columbia, Canada, V0R 1B0.; University of British Columbia, Vancouver, British Columbia, Canada., Rippin L; Department of Integrative Biology, University of Wisconsin-Madison, Madison, Wisconsin, USA., Reyes Contreras E; Department of Biology, Carleton College, Northfield, Minnesota, USA., Redfield E; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA., Polard E; Bamfield Marine Sciences Centre, Bamfield, British Columbia, Canada, V0R 1B0.; University of Victoria, Victoria, British Columbia, Canada., Patterson C; Department of Biology, Carleton College, Northfield, Minnesota, USA., Gilani F; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA., Flanagan J; Department of Biology, Carleton College, Northfield, Minnesota, USA., Dubin S; Department of Biology, Carleton College, Northfield, Minnesota, USA., Cooper P; Department of Biology, Carleton College, Northfield, Minnesota, USA., Codner P; Department of Integrative Biology, University of Wisconsin-Madison, Madison, Wisconsin, USA., Chen A; Department of Biology, Carleton College, Northfield, Minnesota, USA., Casey G; Department of Biology, Carleton College, Northfield, Minnesota, USA., Albright AG; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA., Hite J; Department of Pathobiological Science, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA., Weber JN; Department of Integrative Biology, University of Wisconsin-Madison, Madison, Wisconsin, USA., Bolnick DI; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA., Hund AK; Department of Biology, Carleton College, Northfield, Minnesota, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 04. Date of Electronic Publication: 2026 May 04.
Publication Type: Journal Article; Preprint
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  Data: Constitutive and inducible fibrosis explain immune variation among threespine stickleback populations.
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  Data: <searchLink fieldCode="AU" term="%22Choi+ES%22">Choi ES</searchLink>; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.; These authors contributed equally to this work.; Lead contact.<br /><searchLink fieldCode="AU" term="%22Flanagan+BA%22">Flanagan BA</searchLink>; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.; These authors contributed equally to this work.<br /><searchLink fieldCode="AU" term="%22Alexander+H%22">Alexander H</searchLink>; Bamfield Marine Sciences Centre, Bamfield, British Columbia, Canada, V0R 1B0.<br /><searchLink fieldCode="AU" term="%22Berini+J%22">Berini J</searchLink>; Department of Biology, Carleton College, Northfield, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Yeung+A%22">Yeung A</searchLink>; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.<br /><searchLink fieldCode="AU" term="%22Wolf+CJ%22">Wolf CJ</searchLink>; Department of Integrative Biology, University of Wisconsin-Madison, Madison, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Watts+V%22">Watts V</searchLink>; Bamfield Marine Sciences Centre, Bamfield, British Columbia, Canada, V0R 1B0.; University of Victoria, Victoria, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Vaziri+G%22">Vaziri G</searchLink>; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.; Current address: University of Minnesota.<br /><searchLink fieldCode="AU" term="%22Vargas+N%22">Vargas N</searchLink>; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.<br /><searchLink fieldCode="AU" term="%22Szajada+C%22">Szajada C</searchLink>; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.<br /><searchLink fieldCode="AU" term="%22Steffen+P%22">Steffen P</searchLink>; Department of Biology, Carleton College, Northfield, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Srinivas+I%22">Srinivas I</searchLink>; Department of Pathobiological Science, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Shahid+M%22">Shahid M</searchLink>; Department of Biology, Carleton College, Northfield, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Santacruz+A%22">Santacruz A</searchLink>; Stowers Institute for Medical Research, Kansas City, MO, USA.; Current address: Institute for Integrative Cell Biology and Physiology, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Rochon+K%22">Rochon K</searchLink>; Bamfield Marine Sciences Centre, Bamfield, British Columbia, Canada, V0R 1B0.; University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Rippin+L%22">Rippin L</searchLink>; Department of Integrative Biology, University of Wisconsin-Madison, Madison, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Reyes+Contreras+E%22">Reyes Contreras E</searchLink>; Department of Biology, Carleton College, Northfield, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Redfield+E%22">Redfield E</searchLink>; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.<br /><searchLink fieldCode="AU" term="%22Polard+E%22">Polard E</searchLink>; Bamfield Marine Sciences Centre, Bamfield, British Columbia, Canada, V0R 1B0.; University of Victoria, Victoria, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Patterson+C%22">Patterson C</searchLink>; Department of Biology, Carleton College, Northfield, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Gilani+F%22">Gilani F</searchLink>; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.<br /><searchLink fieldCode="AU" term="%22Flanagan+J%22">Flanagan J</searchLink>; Department of Biology, Carleton College, Northfield, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Dubin+S%22">Dubin S</searchLink>; Department of Biology, Carleton College, Northfield, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Cooper+P%22">Cooper P</searchLink>; Department of Biology, Carleton College, Northfield, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Codner+P%22">Codner P</searchLink>; Department of Integrative Biology, University of Wisconsin-Madison, Madison, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Chen+A%22">Chen A</searchLink>; Department of Biology, Carleton College, Northfield, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Casey+G%22">Casey G</searchLink>; Department of Biology, Carleton College, Northfield, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Albright+AG%22">Albright AG</searchLink>; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.<br /><searchLink fieldCode="AU" term="%22Hite+J%22">Hite J</searchLink>; Department of Pathobiological Science, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Weber+JN%22">Weber JN</searchLink>; Department of Integrative Biology, University of Wisconsin-Madison, Madison, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Bolnick+DI%22">Bolnick DI</searchLink>; Department of Ecology and Evolutionary Biology, University of Connecticut, 75 North Eagleville Rd, Storrs CT 06269 USA.<br /><searchLink fieldCode="AU" term="%22Hund+AK%22">Hund AK</searchLink>; Department of Biology, Carleton College, Northfield, Minnesota, USA.
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