A mycobacterial Sec61 inhibitor disrupts lysosome function by blocking Vacuolar-ATPase biosynthesis.
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| Title: | A mycobacterial Sec61 inhibitor disrupts lysosome function by blocking Vacuolar-ATPase biosynthesis. |
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| Authors: | Hall BS; Discipline of Microbes, Infection and Immunity, School of Bioscience and Medicine, Faculty of Health and Medical Science, University of Surrey, Guildford, UK. Electronic address: b.s.hall@surrey.ac.uk., Owusu-Boateng K; Discipline of Microbes, Infection and Immunity, School of Bioscience and Medicine, Faculty of Health and Medical Science, University of Surrey, Guildford, UK., McPhail KL; Department of Medicinal Chemistry, L. S. Skaggs Pharmacy Institute, Salt Lake City, UT, USA., Shi WQ; Department of Chemistry, Ball State University, Muncie, IN, USA., Simmonds RE; Discipline of Microbes, Infection and Immunity, School of Bioscience and Medicine, Faculty of Health and Medical Science, University of Surrey, Guildford, UK. |
| Source: | European journal of cell biology [Eur J Cell Biol] 2026 Apr 21; Vol. 105 (3), pp. 151541. Date of Electronic Publication: 2026 Apr 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: Germany NLM ID: 7906240 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-1298 (Electronic) Linking ISSN: 01719335 NLM ISO Abbreviation: Eur J Cell Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1618-1298 |
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| DOI: | 10.1016/j.ejcb.2026.151541 |