A broadly-neutralizing antibody against Orthoebolavirus glycoprotein that potentiates the breadth and neutralization of other antibodies.
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| Title: | A broadly-neutralizing antibody against Orthoebolavirus glycoprotein that potentiates the breadth and neutralization of other antibodies. |
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| Authors: | Donnellan FR; Department of Biochemistry, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, Old Road Campus Research Building, University of Oxford, Oxford, UK.; Department of Paediatrics, University of Oxford, Oxford, UK., Rayaprolu V; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA.; Pacific Northwest Cryo-EM Center, Oregon Health and Sciences University, Portland, OR, USA., Rijal P; CAMS Oxford Institute, Chinese Academy of Medical Sciences & Peking Union Medical College, University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK., O'Dowd V; UCB Pharma, Slough, UK., Parvate A; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA.; Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA., Callaway H; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA.; Chemistry & Biochemistry Building, Montana State University, Bozeman, MT, USA., Hariharan C; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA., Parekh D; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA., Hui S; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA.; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA., Shaffer KCL; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA.; Department of Medicine, University of California San Diego, La Jolla, CA, USA., Avalos RD; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA., Hastie KM; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA., Schimanski L; MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK., Müller-Kräuter H; Institute of Virology, Philipps University Marburg, Marburg, Germany., Strecker T; Institute of Virology, Philipps University Marburg, Marburg, Germany., Balaram A; Influenza Research Institute, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA., Halfmann P; Influenza Research Institute, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA., Saphire EO; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA.; Department of Medicine, University of California San Diego, La Jolla, CA, USA., Lightwood DJ; UCB Pharma, Slough, UK., Townsend AR; CAMS Oxford Institute, Chinese Academy of Medical Sciences & Peking Union Medical College, University of Oxford, Oxford, UK.; MRC Translational Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK., Draper SJ; Department of Biochemistry, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK. simon.draper@paediatrics.ox.ac.uk.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK. simon.draper@paediatrics.ox.ac.uk.; The Jenner Institute, Old Road Campus Research Building, University of Oxford, Oxford, UK. simon.draper@paediatrics.ox.ac.uk.; NIHR Oxford Biomedical Research Centre, Oxford, UK. simon.draper@paediatrics.ox.ac.uk.; Department of Paediatrics, University of Oxford, Oxford, UK. simon.draper@paediatrics.ox.ac.uk. |
| Source: | Npj viruses [Npj Viruses] 2026 May 07; Vol. 4 (1). Date of Electronic Publication: 2026 May 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Portfolio, Springer Nature Country of Publication: England NLM ID: 9918716188906676 Publication Model: Electronic Cited Medium: Internet ISSN: 2948-1767 (Electronic) Linking ISSN: 29481767 NLM ISO Abbreviation: Npj Viruses Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2948-1767 |
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| DOI: | 10.1038/s44298-026-00192-7 |
