Stiripentol induces ER stress and pyroptosis in pancreatic cancer cells under metabolic stress by dysregulating SFAs/UFAs homeostasis.

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Title: Stiripentol induces ER stress and pyroptosis in pancreatic cancer cells under metabolic stress by dysregulating SFAs/UFAs homeostasis.
Authors: Ding J; Department of Oncology, Shanghai East Hospital, School of Medicine, Tongji University, No. 1800 Yuntai Rd, Shanghai, 200123, China., Pan J; Department of Oncology, Shanghai East Hospital, School of Medicine, Tongji University, No. 1800 Yuntai Rd, Shanghai, 200123, China.; Hubei University of Medicine, Shiyan, Hubei Province, 442000, China., Xue W; Tongji University School of Medicine, No. 500 Zhennan Rd, Shanghai, 200331, China., Ying S; Tongji University School of Medicine, No. 500 Zhennan Rd, Shanghai, 200331, China., Zuo S; Tongji University School of Medicine, No. 500 Zhennan Rd, Shanghai, 200331, China., Xia R; Tongji University School of Medicine, No. 500 Zhennan Rd, Shanghai, 200331, China., Li Y; Department of Oncology, Shanghai East Hospital, School of Medicine, Tongji University, No. 1800 Yuntai Rd, Shanghai, 200123, China., Quan M; Department of Oncology, Shanghai East Hospital, School of Medicine, Tongji University, No. 1800 Yuntai Rd, Shanghai, 200123, China. mquan@tongji.edu.cn.
Source: Cellular oncology (Dordrecht, Netherlands) [Cell Oncol (Dordr)] 2026 May 08; Vol. 49 (4). Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 101552938 Publication Model: Electronic Cited Medium: Internet ISSN: 2211-3436 (Electronic) Linking ISSN: 22113428 NLM ISO Abbreviation: Cell Oncol (Dordr) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Stiripentol induces ER stress and pyroptosis in pancreatic cancer cells under metabolic stress by dysregulating SFAs/UFAs homeostasis.
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  Data: <searchLink fieldCode="AU" term="%22Ding+J%22">Ding J</searchLink>; Department of Oncology, Shanghai East Hospital, School of Medicine, Tongji University, No. 1800 Yuntai Rd, Shanghai, 200123, China.<br /><searchLink fieldCode="AU" term="%22Pan+J%22">Pan J</searchLink>; Department of Oncology, Shanghai East Hospital, School of Medicine, Tongji University, No. 1800 Yuntai Rd, Shanghai, 200123, China.; Hubei University of Medicine, Shiyan, Hubei Province, 442000, China.<br /><searchLink fieldCode="AU" term="%22Xue+W%22">Xue W</searchLink>; Tongji University School of Medicine, No. 500 Zhennan Rd, Shanghai, 200331, China.<br /><searchLink fieldCode="AU" term="%22Ying+S%22">Ying S</searchLink>; Tongji University School of Medicine, No. 500 Zhennan Rd, Shanghai, 200331, China.<br /><searchLink fieldCode="AU" term="%22Zuo+S%22">Zuo S</searchLink>; Tongji University School of Medicine, No. 500 Zhennan Rd, Shanghai, 200331, China.<br /><searchLink fieldCode="AU" term="%22Xia+R%22">Xia R</searchLink>; Tongji University School of Medicine, No. 500 Zhennan Rd, Shanghai, 200331, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Oncology, Shanghai East Hospital, School of Medicine, Tongji University, No. 1800 Yuntai Rd, Shanghai, 200123, China.<br /><searchLink fieldCode="AU" term="%22Quan+M%22">Quan M</searchLink>; Department of Oncology, Shanghai East Hospital, School of Medicine, Tongji University, No. 1800 Yuntai Rd, Shanghai, 200123, China. mquan@tongji.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101552938%22">Cellular oncology (Dordrecht, Netherlands)</searchLink> [Cell Oncol (Dordr)] 2026 May 08; Vol. 49 (4). <i>Date of Electronic Publication: </i>2026 May 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101552938 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2211-3436 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222113428%22">22113428 </searchLink><i>NLM ISO Abbreviation: </i>Cell Oncol (Dordr) <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s13402-026-01205-6
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        Text: English
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      – TitleFull: Stiripentol induces ER stress and pyroptosis in pancreatic cancer cells under metabolic stress by dysregulating SFAs/UFAs homeostasis.
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            NameFull: Ding J
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            NameFull: Pan J
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            – D: 08
              M: 05
              Text: 2026 May 08
              Type: published
              Y: 2026
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              Value: 2211-3436
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              Value: 49
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            – TitleFull: Cellular oncology (Dordrecht, Netherlands)
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