Intravitreal AAV vector delivery induces integrin-dependent ocular inflammation, complement activation, and antiviral and DNA damage responses.
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| Title: | Intravitreal AAV vector delivery induces integrin-dependent ocular inflammation, complement activation, and antiviral and DNA damage responses. |
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| Authors: | Costa-Verdera H; Immunology, Spark Therapeutics, Philadelphia, PA, United States.; Ocular Research, Spark Therapeutics, Philadelphia, PA, United States., Jamwal D; Immunology, Spark Therapeutics, Philadelphia, PA, United States., Fabyanic E; Genomics and Data Science, Spark Therapeutics, Philadelphia, PA, United States., Hippen A; Genomics and Data Science, Spark Therapeutics, Philadelphia, PA, United States., Salvatore M; Immunology, Spark Therapeutics, Philadelphia, PA, United States., Du A; Non-clinical Research Operations, Spark Therapeutics, Philadelphia, PA, United States., Majowicz A; Immunology, Spark Therapeutics, Philadelphia, PA, United States., Markusic D; Immunology, Spark Therapeutics, Philadelphia, PA, United States., Chatterton JE; Ocular Research, Spark Therapeutics, Philadelphia, PA, United States., Haurigot V; Ocular Research, Spark Therapeutics, Philadelphia, PA, United States., Kuranda K; Immunology, Spark Therapeutics, Philadelphia, PA, United States. |
| Source: | Frontiers in immunology [Front Immunol] 2026 Apr 22; Vol. 17, pp. 1799327. Date of Electronic Publication: 2026 Apr 22 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2026.1799327 |
