Adaption of the plasmin generation assay to enhance sensitivity to plasminogen activator inhibitor-1 and establishment of sex-specific reference values in human plasma.

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Title: Adaption of the plasmin generation assay to enhance sensitivity to plasminogen activator inhibitor-1 and establishment of sex-specific reference values in human plasma.
Authors: De Simone I; Synapse Research Institute, Maastricht, The Netherlands., Pocknell K; Aberdeen Cardiovascular and Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., Tufaha S; Synapse Research Institute, Maastricht, The Netherlands.; Aberdeen Cardiovascular and Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., Konings J; Synapse Research Institute, Maastricht, The Netherlands., Roest M; Synapse Research Institute, Maastricht, The Netherlands., Wolberg AS; Department of Pathology and Laboratory Medicine and UNC Blood Research Center, University of North Carolina at Chapel Hill, North Carolina, USA., Whyte CS; Aberdeen Cardiovascular and Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., Mutch NJ; Aberdeen Cardiovascular and Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., de Laat B; Synapse Research Institute, Maastricht, The Netherlands., Huskens D; Synapse Research Institute, Maastricht, The Netherlands.
Source: Research and practice in thrombosis and haemostasis [Res Pract Thromb Haemost] 2026 Mar 25; Vol. 10 (3), pp. 103435. Date of Electronic Publication: 2026 Mar 25 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101703775 Publication Model: eCollection Cited Medium: Internet ISSN: 2475-0379 (Electronic) Linking ISSN: 24750379 NLM ISO Abbreviation: Res Pract Thromb Haemost Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2475-0379
DOI:10.1016/j.rpth.2026.103435