A platinum butterfly effect: small changes turn an anticancer drug into a non-toxic metalloantibiotic with in vivo efficacy.
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| Title: | A platinum butterfly effect: small changes turn an anticancer drug into a non-toxic metalloantibiotic with in vivo efficacy. |
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| Authors: | Özsan Ç; Department of Chemistry, Biochemistry & Pharmaceutical Sciences, University of Bern, Bern, Switzerland.; Department of Chemistry, University of York, York, UK., Schäfer AB; Division of Molecular Bioscience, Department of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden.; Center for Antibiotic Resistance Research in Gothenburg (CARe), Gothenburg, Sweden., Akhir A; Department of Molecular Microbiology and Immunology, CSIR-Central Drug Research Institute, Lucknow, India., Aning OA; Division of Molecular Bioscience, Department of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden.; Center for Antibiotic Resistance Research in Gothenburg (CARe), Gothenburg, Sweden., Fulgencio S; Department of Chemistry, Biochemistry & Pharmaceutical Sciences, University of Bern, Bern, Switzerland., Maitra R; Department of Molecular Microbiology and Immunology, CSIR-Central Drug Research Institute, Lucknow, India., Rani R; Division of Molecular Bioscience, Department of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden.; Center for Antibiotic Resistance Research in Gothenburg (CARe), Gothenburg, Sweden., Saxena D; Department of Molecular Microbiology and Immunology, CSIR-Central Drug Research Institute, Lucknow, India., Westerlund F; Division of Molecular Bioscience, Department of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden.; Center for Antibiotic Resistance Research in Gothenburg (CARe), Gothenburg, Sweden., Chopra S; Department of Molecular Microbiology and Immunology, CSIR-Central Drug Research Institute, Lucknow, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Wenzel M; Division of Molecular Bioscience, Department of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden. wenzelm@chalmers.se.; Center for Antibiotic Resistance Research in Gothenburg (CARe), Gothenburg, Sweden. wenzelm@chalmers.se., Frei A; Department of Chemistry, Biochemistry & Pharmaceutical Sciences, University of Bern, Bern, Switzerland. angelo.frei@york.ac.uk.; Department of Chemistry, University of York, York, UK. angelo.frei@york.ac.uk. |
| Source: | Npj antimicrobials and resistance [NPJ Antimicrob Resist] 2026 May 08; Vol. 4 (1). Date of Electronic Publication: 2026 May 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Portfolio Country of Publication: England NLM ID: 9918804282606676 Publication Model: Electronic Cited Medium: Internet ISSN: 2731-8745 (Electronic) Linking ISSN: 27318745 NLM ISO Abbreviation: NPJ Antimicrob Resist Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2731-8745 |
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| DOI: | 10.1038/s44259-026-00211-w |
