Metformin inhibits mitochondrial complex I in intestinal epithelium to promote glycaemic control.

Saved in:
Bibliographic Details
Title: Metformin inhibits mitochondrial complex I in intestinal epithelium to promote glycaemic control.
Authors: Sebo ZL; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. zachary.sebo@northwestern.edu., Chakrabarty RP; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Grant RA; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., D'Alessandro KB; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Koss AR; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Blum JLE; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Davidson SM; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Reczek CR; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Chandel NS; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. nav@northwestern.edu.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. nav@northwestern.edu.; Chan Zuckerberg Biohub, Chicago, IL, USA. nav@northwestern.edu.
Source: Nature metabolism [Nat Metab] 2026 Jun; Vol. 8 (6), pp. 1291-1304. Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2522-5812
DOI:10.1038/s42255-026-01530-y