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Proteomic and degradomic signatures of extracellular matrix remodeling in calcific aortic valve stenosis.

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Title: Proteomic and degradomic signatures of extracellular matrix remodeling in calcific aortic valve stenosis.
Authors: Iacobucci I; Department of Chemical Sciences, University of Naples 'Federico II', Strada Comunale Cinthia, 21, Naples, 80126, Italy. ilaria.iacobucci@unina.it., Monaco V; Department of Chemical Sciences, University of Naples 'Federico II', Strada Comunale Cinthia, 21, Naples, 80126, Italy., Lobianco AL; Department of Chemical Sciences, University of Naples 'Federico II', Strada Comunale Cinthia, 21, Naples, 80126, Italy., Cipolletta B; Department of Chemical Sciences, University of Naples 'Federico II', Strada Comunale Cinthia, 21, Naples, 80126, Italy., Birolo L; Department of Chemical Sciences, University of Naples 'Federico II', Strada Comunale Cinthia, 21, Naples, 80126, Italy., Conte M; Department of Translational Medical Sciences, University of Napoli 'Federico II', Via Pansini, 5, Naples, 80131, Italy., Myasoedova VA; Applied Biotechnology in Cardiovascular Inflammation Unit, Centro Cardiologico Monzino IRCCS, Milan, Italy.; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy., Valerio V; Applied Biotechnology in Cardiovascular Inflammation Unit, Centro Cardiologico Monzino IRCCS, Milan, Italy.; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy., Poggio P; Applied Biotechnology in Cardiovascular Inflammation Unit, Centro Cardiologico Monzino IRCCS, Milan, Italy. paolo.poggio@cardiologicomonzino.it.; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy. paolo.poggio@cardiologicomonzino.it., Parisi V; Department of Translational Medical Sciences, University of Napoli 'Federico II', Via Pansini, 5, Naples, 80131, Italy., Monti M; Department of Chemical Sciences, University of Naples 'Federico II', Strada Comunale Cinthia, 21, Naples, 80126, Italy.
Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2026 May 08; Vol. 32 (1). Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1528-3658
DOI:10.1186/s10020-026-01499-0