Comparative Effectiveness and Safety of Tofacitinib, Filgotinib, and Upadacitinib in Ulcerative Colitis: A Multicenter Real-World Cohort Study.
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| Title: | Comparative Effectiveness and Safety of Tofacitinib, Filgotinib, and Upadacitinib in Ulcerative Colitis: A Multicenter Real-World Cohort Study. |
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| Authors: | Tursi A; Territorial Gastroenterology Service, ASL BAT, Andria, Italy.; Department of Medical and Surgical Sciences, School of Medicine, Catholic University, Rome, Italy., Pasta A; Department of Internal Medicine and Medical Specialties, Division of Gastroenterology, IRCCS 'San Martino'' Hospital, University of Genoa, Genoa, Italy., Elisei W; Division of Gastroenterology, A.O. 'S. Camillo-Forlanini', Rome, Italy., Barberio B; Gastroenterology Unit, Azienda Ospedale-Università Di Padova (AOUP), Padua, Italy., Mocci G; Division of Gastroenterology, AORN 'Brotzu' Hospital, Cagliari, Italy., Savarino EV; Gastroenterology Unit, Azienda Ospedale-Università Di Padova (AOUP), Padua, Italy., de Barba C; Gastroenterology Unit, Azienda Ospedale-Università Di Padova (AOUP), Padua, Italy., Maconi G; Gastroenterology Unit, Department Biomedical and Clinical Sciences, 'L. Sacco' University Hospital, Milan, Italy., Cataletti G; Gastroenterology Unit, Department Biomedical and Clinical Sciences, 'L. Sacco' University Hospital, Milan, Italy., Scaldaferri F; Digestive Diseases Centre (CEMAD), Department of Medical and Surgical Sciences, Policlinico Universitario 'A. Gemelli' Foundation, IRCCS Largo Francesco Vito, 1, 00168, Rome, Italy.; School of Medicine, Catholic University, Rome, Italy., Napolitano D; Digestive Diseases Centre (CEMAD), Department of Medical and Surgical Sciences, Policlinico Universitario 'A. Gemelli' Foundation, IRCCS Largo Francesco Vito, 1, 00168, Rome, Italy., Costa F; IBD Unit, Department of General Surgery and Gastroenterology, Pisa University Hospital, Pisa, Italy., Ceccarelli L; IBD Unit, Department of General Surgery and Gastroenterology, Pisa University Hospital, Pisa, Italy., Marzo M; Division of Gastroenterology, 'Veris-Delli Ponti' Hospital, Scorrano, LE, Italy., Monterubbianesi R; Division of Gastroenterology, A.O. 'S. Camillo-Forlanini', Rome, Italy., di Fonzo M; Division of Gastroenterology, A.O. 'S. Camillo-Forlanini', Rome, Italy., Lombardi G; Division of Gastroenterology, AORN 'Cardarelli', Naples, Italy., Patturelli M; Division of Gastroenterology, AORN 'Cardarelli', Naples, Italy., Ribaldone DG; Department of Medical Sciences, Division of Gastroenterology, IBD Unit, 'A.O.U. Citta Della Salute e Della Scienza Di Torino'', University of Turin, Turin, Italy., Bertani L; Division of Gastroenterology, 'Felice Lotti' Hospital, Azienda USL Toscana Nord Ovest, Pontedera, PI, Italy., Rodino' S; Division of Gastroenterology, 'Ciaccio-Pugliese' Hospital, Catanzaro, Italy., Sebkova L; Division of Gastroenterology, 'Ciaccio-Pugliese' Hospital, Catanzaro, Italy., Bodini G; Department of Internal Medicine and Medical Specialties, Division of Gastroenterology, IRCCS 'San Martino'' Hospital, University of Genoa, Genoa, Italy., Pranzo G; Ambulatory for IBD Treatment, 'Valle D'Itria' Hospital, Martina Franca, TA, Italy., Serio M; Division of Gastroenterology, 'San Salvatore' Hospital, Pesaro, Italy., Scarcelli A; Division of Gastroenterology, 'San Salvatore' Hospital, Pesaro, Italy., Luppino I; Division of Gastroenterology, 'Annunziata' Hospital, Cosenza, Italy., Ferronato A; Digestive Endoscopy Unit, ULSS7 Pedemontana, Santorso, VI, Italy., Spagnuolo R; Department of Health Science, University of Catanzaro, Catanzaro, Italy., Luzza F; Department of Health Science, University of Catanzaro, Catanzaro, Italy., Morano D; Department of Health Science, University of Catanzaro, Catanzaro, Italy., Gravina AG; Department of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania 'Luigi Vanvitelli'', Naples, Italy., Pellegrino R; Department of Precision Medicine, Hepatogastroenterology and Digestive Endoscopy Unit, University of Campania 'Luigi Vanvitelli'', Naples, Italy., Vespere G; Division of Gastroenterology, 'Ospedale del Mare', ASL Na1, Naples, Italy., Sedda S; Division of Gastroenterology, 'Ospedale del Mare', ASL Na1, Naples, Italy., Allegretta L; Division of Gastroenterology, 'Santa Caterina Novella' Hospital, Galatina (LE), Italy., Fanigliulo L; Division of Gastroenterology, 'S.S. Annunziata' Hospital, Taranto, Italy., Grossi L; Gastroenterology Unit, 'Spirito Santo' Hospital, 'G d'Annunzio' University, Pescara, Italy., Cortellini F; Division of Gastroenterology, 'Infermi' Hospital, Rimini, Italy., Forti G; Division of Digestive Endoscopy, 'S. Maria Goretti' Hospital, Latina, Italy., Neve V; Division of Gastroenterology, 'A. Perrino' Hospital, Brindisi, Italy., Piergallini S; Division of Gastroenterology, IBD Unit, 'A. Murri' Hospital, Fermo, Italy., Scarozza P; Division of Gastroenterology, 'Ospedale Dei Castelli', Ariccia, Rome, Italy., Bevevino G; Division of Gastroenterology, 'Ospedale Dei Castelli', Ariccia, Rome, Italy., Iacopini F; Division of Gastroenterology, 'Ospedale Dei Castelli', Ariccia, Rome, Italy., Capone P; Division of Gastroenterology, 'T. Maresca' Hospital, Torre del Greco, NA, Italy., Gaiani F; Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy., Kayali S; Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy., Mucherino C; Division of Gastroenterology, Azienda Ospedaliera 'S. Anna E S. Sebastiano', Caserta, Italy., D'antonio E; Division of Gastroenterology, Azienda Ospedaliera 'S. Anna E S. Sebastiano', Caserta, Italy., D'ascoli B; Division of Gastroenterology, 'Madonna Delle Grazie' Hospital, Matera, Italy., Colucci R; Digestive Endoscopy Unit, 'San Matteo Degli Infermi' Hospital, Spoleto, PG, Italy., Bachetti F; Digestive Endoscopy Unit, 'San Matteo Degli Infermi' Hospital, Spoleto, PG, Italy., Giorgetti GM; Clinical Nutrition and Digestive Endoscopy Unit, 'S. Eugenio' Hospital, Rome, Italy., Clemente V; Clinical Nutrition and Digestive Endoscopy Unit, 'S. Eugenio' Hospital, Rome, Italy., Pagnini C; Division of Gastroenterology, 'S. Giovanni-Addolorata' Hospital, Rome, Italy., Cuomo A; Division of Gastroenterology, Umberto I' Hospital, Nocera Inferiore, SA, Italy., Donnarumma L; Division of Gastroenterology, Umberto I' Hospital, Nocera Inferiore, SA, Italy., Onidi FM; Division of Gastroenterology, AORN 'Brotzu' Hospital, Cagliari, Italy., Satta PU; Division of Gastroenterology, AORN 'Brotzu' Hospital, Cagliari, Italy., Picchio M; Division of General Surgery, 'P. Colombo' Hospital, ASL Roma 6, Velletri, Rome, Italy., Papa A; Digestive Diseases Centre (CEMAD), Department of Medical and Surgical Sciences, Policlinico Universitario 'A. Gemelli' Foundation, IRCCS Largo Francesco Vito, 1, 00168, Rome, Italy. alfredo.papa@unicatt.it.; School of Medicine, Catholic University, Rome, Italy. alfredo.papa@unicatt.it. |
| Corporate Authors: | Italian Network for Inflammatory Bowel Diseases (IN-IBD) |
| Source: | Advances in therapy [Adv Ther] 2026 Jul; Vol. 43 (7), pp. 3165-3186. Date of Electronic Publication: 2026 May 09. |
| Publication Type: | Journal Article; Multicenter Study; Comparative Study |
| Journal Info: | Publisher: Health Communications Inc Country of Publication: United States NLM ID: 8611864 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-8652 (Electronic) Linking ISSN: 0741238X NLM ISO Abbreviation: Adv Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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