Endovascular treatment for medium or distal vessel occlusion stroke (DISTAL): 12-month outcomes of a multicentre, open-label, randomised trial.

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Title: Endovascular treatment for medium or distal vessel occlusion stroke (DISTAL): 12-month outcomes of a multicentre, open-label, randomised trial.
Authors: Fischer U; Department of Neurology, Inselspital Bern, University Hospital Bern, Bern, Switzerland; University of Bern, Bern, Switzerland. Electronic address: urs.fischer@insel.ch., Brehm A; Department of Diagnostic and Interventional Neuroradiology, University Hospital Basel, Basel, Switzerland., Ribo M; Department of Neurology, Hospital Vall d'Hebron, Barcelona, Spain., Rizzo F; Department of Neurology, Hospital Vall d'Hebron, Barcelona, Spain., Strbian D; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Räty S; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Arenillas JF; Stroke Program, Department of Neurology, Hospital Clínico Universitario Valladolid, IBIOVALL, Spain; Clinical Neurosciences Research Group, Department of Medicine, University of Valladolid, IBGM, Consejo Superior de Investigaciones Científicas (CSIC) - Universidad de Valladolid, Valladolid, Spain., Martínez-Galdámez M; Neuroradiology Unit, Department of Radiology, Hospital Clínico Universitario Valladolid, IBIOVALL, Valladolid, Spain., Hajdu SD; Department of Diagnostic and Interventional Neuroradiology, Lausanne University Hospital, Lausanne, Switzerland., Michel P; Department of Neurology, Lausanne University Hospital, Lausanne, Switzerland., Gralla J; Department of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, Bern, Switzerland., Piechowiak EI; Department of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, Bern, Switzerland., Kaiser DPO; Institute of Neuroradiology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Dresden Neurovascular Center, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Puetz V; Dresden Neurovascular Center, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Department of Neurology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Van den Bergh F; Department of Radiology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium., De Raedt S; Department of Neurology, Universitair Ziekenhuis Brussel (UZ Brussel), NEUR Research Group, Vrije Universiteit Brussel (VUB), Brussels, Belgium., Bellante F; Department of Neurology, Hôpital Civil Marie Curie, CHU Charleroi, Charleroi, Belgium., Dusart A; Department of Neurology, Hôpital Civil Marie Curie, CHU Charleroi, Charleroi, Belgium., Hellstern V; Department of Neuroradiology, Kantonsspital St Gallen, St Gallen, Switzerland., Khanafer A; Department of Neuroradiology, Klinikum Stuttgart, Stuttgart, Germany., Parrilla G; Department of Interventional Neuroradiology, University Hospital Virgen de la Arrixaca, El Palmar, Murcia, Spain., Morales A; Department of Interventional Neuroradiology, University Hospital Virgen de la Arrixaca, El Palmar, Murcia, Spain., Kirschke JS; Department of Diagnostic and Interventional Neuroradiology, Technical University of Munich, School of Medicine and Health, Klinikum rechts der Isar, Munich, Germany., Wunderlich S; Department of Neurology, Technical University of Munich, School of Medicine and Health, Klinikum rechts der Isar, Munich, Germany., Fiehler J; Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg Eppendorf, Hamburg, Germany., Thomalla G; Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany., Lemmens R; KU Leuven, Department of Neurosciences, Experimental Neurology; University Hospitals Leuven, Department of Neurology, Leuven, Belgium., Peluso JP; Department of Interventional Neuroradiology, University Hospital Leuven, Leuven, Belgium., Bolognese M; Neurocenter, Cantonal Hospital of Lucerne, Lucerne, Switzerland., von Hessling A; Neurocenter, Cantonal Hospital of Lucerne, Lucerne, Switzerland; Section of Neuroradiology, Neurocenter, Cantonal Hospital of Lucerne, Lucerne, Switzerland., van Es A; Department of Radiology, Leiden University Medical Centre, Leiden, Netherlands; University Neurovascular Center Leiden-the Hague, Leiden, Netherlands., Kruyt ND; Department of Neurology, Leiden University Medical Center, Leiden, Netherlands; University Neurovascular Center Leiden-the Hague, Leiden, Netherlands., Coutinho JM; Department of Neurology, Amsterdam University Medical Center, location University of Amsterdam, Amsterdam, the Netherlands., Castaño C; Department of Interventional Neuroradiology, University Hospital Germans Trias i Pujol, Badalona, Spain., Minnerup J; Department of Neurology, University of Münster, Münster, Germany; Department of Neurology, University of Lübeck, Lübeck, Germany., van Zwam W; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands., Dhondt E; Department of Vascular and Interventional (Neuro-)Radiology (VINRAD), Ghent University Hospital, Ghent, Belgium., Nolte CH; Department of Neurology with Experimental Neurology and Center for Stroke Research Berlin (CSB), Charité - Universitätsmedizin Berlin, Berlin, Germany., Machi P; Division of Diagnostic and Interventional Neuroradiology, Geneva University Hospitals, Geneva, Switzerland., Loehr C; Department of Neuroradiology, Klinikum Vest, Recklinghausen, Germany., Mattle HP; Department of Neurology, Inselspital Bern, University Hospital Bern, Bern, Switzerland., Buhk JH; Department of Neuroradiology, Asklepios Hospital Hamburg St Georg, Hamburg, Germany., Kaesmacher J; Department of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, Bern, Switzerland., Dobrocky T; Department of Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, Bern, Switzerland., Papanagiotou P; Department of Diagnostic and Interventional Neuroradiology, Hospital Bremen Mitte, Bremen, Germany; Department of Radiology, Areteion University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Alonso A; Department of Neurology, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany., Holtmannspoetter M; Department of Diagnostic and Interventional Neuroradiology, Hospital Nuremberg South Campus, Nuremberg, Germany., Zini A; IRCCS Istituto delle Scienze Neurologiche di Bologna, Maggiore Hospital, Bologna, Italy., Renieri L; Interventional Neurovascular Unit, Careggi University Hospital, Florence, Italy., Keil F; Institution of Neuroradiology, University Hospital Frankfurt, Goethe University, Frankfurt, Germany., van den Wijngaard I; Department of Neurology, Leiden University Medical Center, Leiden, Netherlands; University Neurovascular Center Leiden-the Hague, Leiden, Netherlands; Department of Neurology and Radiology, Haaglanden Medical Center, Den Haag, Netherlands., Kägi G; Department of Neurology, Inselspital Bern, University Hospital Bern, Bern, Switzerland., Terceño M; Department of Neurology, Hospital Doctor Josep Trueta, Girona, Spain., Wiesmann M; Department of Diagnostic and Interventional Neuroradiology, University Hospital RWTH Aachen, Aachen, Germany., Amaro S; Department of Neurology, Hospital Clinic Barcelona, Barcelona, Spain., Fragata I; Neuroradiology Department, ULS São José, Lisboa, Portugal., Katan M; Department of Neurology, University Hospital Basel, Basel, Switzerland., Leker RR; Department of Neurology, Hadassah Hebrew University Medical Center, Jerusalem, Israel., Saver JL; Comprehensive Stroke Center and Department of Neurology, David Geffen School of Medicine of UCLA, Los Angeles, CA, USA., Staals J; Department of Neurology and Cardiovascular Research Institute (CARIM), Maastricht University Medical Centre, Maastricht, Netherlands., Rommers N; Department of Clinical Research, University Hospital Basel, Basel, Switzerland., Balmer L; Department of Diagnostic and Interventional Neuroradiology, University Hospital Basel, Basel, Switzerland., Psychogios M; Department of Diagnostic and Interventional Neuroradiology, University Hospital Basel, Basel, Switzerland. Electronic address: marios.psychogios@usb.ch.
Corporate Authors: DISTAL investigators
Source: The Lancet. Neurology [Lancet Neurol] 2026 Jun; Vol. 25 (6), pp. 571-580. Date of Electronic Publication: 2026 May 06.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 101139309 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-4465 (Electronic) Linking ISSN: 14744422 NLM ISO Abbreviation: Lancet Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1474-4465
DOI:10.1016/S1474-4422(26)00169-9