IRE1/p‑JNK/NRF2 axis-mediated GPX4 upregulation underlies ferroptosis resistance in rheumatoid arthritis fibroblast-like synoviocytes.
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| Title: | IRE1/p‑JNK/NRF2 axis-mediated GPX4 upregulation underlies ferroptosis resistance in rheumatoid arthritis fibroblast-like synoviocytes. |
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| Authors: | Liu J; Department of Rheumatology, Peking University First Hospital, Beijing, China., Xie W; Department of Rheumatology, Peking University First Hospital, Beijing, China., Cao Y; Department of Orthopedics, Peking University First Hospital, Beijing, China., Zhang L; Department of Orthopedics, Beijing Jishuitan Hospital, Beijing, China., Geng Y; Department of Rheumatology, Peking University First Hospital, Beijing, China., Zhang Z; Department of Rheumatology, Peking University First Hospital, Beijing, China. zhuoli.zhang@126.com.; Department of Rheumatology and Clinical Immunology, Peking University First Hospital, No.8, Xishiku Street, West District, Beijing, 100034, China. zhuoli.zhang@126.com. |
| Source: | Arthritis research & therapy [Arthritis Res Ther] 2026 May 09; Vol. 28 (1). Date of Electronic Publication: 2026 May 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-6362 (Electronic) Linking ISSN: 14786354 NLM ISO Abbreviation: Arthritis Res Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1478-6362 |
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| DOI: | 10.1186/s13075-026-03827-5 |
