Hypoxia Upregulates RIPK1 via the HIF-1α-JAK-STAT Pathway Leading to Astrocyte Necroptosis to Promote Cavitation After Spinal Cord Injury.

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Title: Hypoxia Upregulates RIPK1 via the HIF-1α-JAK-STAT Pathway Leading to Astrocyte Necroptosis to Promote Cavitation After Spinal Cord Injury.
Authors: Bi H; Trauma Center, the First Affiliated Hospital of Kunming Medical University, Kunming, China., Zhang W; Trauma Center, the First Affiliated Hospital of Kunming Medical University, Kunming, China., Duan H; Trauma Center, the First Affiliated Hospital of Kunming Medical University, Kunming, China., Wang C; Trauma Center, the First Affiliated Hospital of Kunming Medical University, Kunming, China., Shen X; Trauma Center, the First Affiliated Hospital of Kunming Medical University, Kunming, China., Jiang G; Trauma Center, the First Affiliated Hospital of Kunming Medical University, Kunming, China., Xue H; Trauma Center, the First Affiliated Hospital of Kunming Medical University, Kunming, China., Yan R; Trauma Center, the First Affiliated Hospital of Kunming Medical University, Kunming, China., Xu Y; Trauma Center, the First Affiliated Hospital of Kunming Medical University, Kunming, China., Zhang Y; Trauma Center, the First Affiliated Hospital of Kunming Medical University, Kunming, China., Zhao H; Trauma Center, the First Affiliated Hospital of Kunming Medical University, Kunming, China., He F; Kunming Medical University Affiliated Qujing Hospital, Qujing, China., Wang Z; Trauma Center, the First Affiliated Hospital of Kunming Medical University, Kunming, China.
Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2026 May; Vol. 32 (5), pp. e70895.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949 (Electronic) Linking ISSN: 17555930 NLM ISO Abbreviation: CNS Neurosci Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1755-5949
DOI:10.1002/cns.70895