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Dose-dependent protective effects of Tripterygium wilfordii glycosides on joint and lung injury and gut microbiota remodeling in collagen-induced arthritis rats.

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Title: Dose-dependent protective effects of Tripterygium wilfordii glycosides on joint and lung injury and gut microbiota remodeling in collagen-induced arthritis rats.
Authors: Qi S; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.; First Clinical Medical College, Henan University of Chinese Medicine, Zhengzhou, Henan, China., Xing Q; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.; Huixian County Hospital of Traditional Chinese Medicine, Xinxiang, Henan, China., Gong X; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China., Jiang Y; First Clinical Medical College, Henan University of Chinese Medicine, Zhengzhou, Henan, China.; Department of Gastroenterology, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China., Zhao Z; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China., Feng Z; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.; First Clinical Medical College, Henan University of Chinese Medicine, Zhengzhou, Henan, China., Jiao S; Henan Provincial Hospital of Traditional Chinese Medicine (The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine), Zhengzhou, Henan, China.; The Second Clinical Medical College of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, China., Wang C; Henan Provincial Hospital of Traditional Chinese Medicine (The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine), Zhengzhou, Henan, China.; The Second Clinical Medical College of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, China., Li S; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China., Li H; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.; First Clinical Medical College, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2026 Apr 23; Vol. 17, pp. 1783503. Date of Electronic Publication: 2026 Apr 23 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Dose-dependent protective effects of Tripterygium wilfordii glycosides on joint and lung injury and gut microbiota remodeling in collagen-induced arthritis rats.
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  Data: <searchLink fieldCode="AU" term="%22Qi+S%22">Qi S</searchLink>; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.; First Clinical Medical College, Henan University of Chinese Medicine, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Xing+Q%22">Xing Q</searchLink>; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.; Huixian County Hospital of Traditional Chinese Medicine, Xinxiang, Henan, China.<br /><searchLink fieldCode="AU" term="%22Gong+X%22">Gong X</searchLink>; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; First Clinical Medical College, Henan University of Chinese Medicine, Zhengzhou, Henan, China.; Department of Gastroenterology, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Zhao+Z%22">Zhao Z</searchLink>; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Feng+Z%22">Feng Z</searchLink>; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.; First Clinical Medical College, Henan University of Chinese Medicine, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Jiao+S%22">Jiao S</searchLink>; Henan Provincial Hospital of Traditional Chinese Medicine (The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine), Zhengzhou, Henan, China.; The Second Clinical Medical College of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Henan Provincial Hospital of Traditional Chinese Medicine (The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine), Zhengzhou, Henan, China.; The Second Clinical Medical College of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Rheumatology and Immunology, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.; First Clinical Medical College, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
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  Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2026 Apr 23; Vol. 17, pp. 1783503. <i>Date of Electronic Publication: </i>2026 Apr 23 (<i>Print Publication: </i>2026).
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              Text: 2026 Apr 23
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