Single-cell and spatial omics in liver identify cell-cell communication regulators in aging and insulin resistance.
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| Title: | Single-cell and spatial omics in liver identify cell-cell communication regulators in aging and insulin resistance. |
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| Authors: | Zhao W; Department of Mathematics and the NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, USA; Diabetes Center, University of California Irvine, Irvine, CA, USA., Jiao X; Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA., Du K; Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA., Sun Q; Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA., Duan J; Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Biological Chemistry, University of California, Irvine, Irvine, CA, USA., Cao Y; Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA., Shen X; Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA., Said Z; Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA., Karri SS; Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Biological Chemistry, University of California, Irvine, Irvine, CA, USA., Ellsworth P; Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA., Hu W; Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA., Sargsyan A; Duke Molecular Physiology Institute, Duke University, Durham, NC, USA., Astapova I; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX, USA., Kim SY; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Gonzalez J; Department of Pathology, Yale School of Medicine, New Haven, CT, USA., Higgins-Chen AT; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Perry RJ; Department of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT, USA., Seki E; Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Herman MA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX, USA., Andersen B; Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Biological Chemistry, University of California, Irvine, Irvine, CA, USA., Nie Q; Department of Mathematics and the NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, USA; Diabetes Center, University of California Irvine, Irvine, CA, USA; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA. Electronic address: qnie@uci.edu., Yang Q; Diabetes Center, University of California Irvine, Irvine, CA, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of California, Irvine, Irvine, CA, USA; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA. Electronic address: qin.yang@uci.edu. |
| Source: | Metabolism: clinical and experimental [Metabolism] 2026 Aug; Vol. 181, pp. 156630. Date of Electronic Publication: 2026 May 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0375267 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8600 (Electronic) Linking ISSN: 00260495 NLM ISO Abbreviation: Metabolism Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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