Optogenetic activation of liver-innervating vagal sensory neurons increases anxiety-like behavior in mice.

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Title: Optogenetic activation of liver-innervating vagal sensory neurons increases anxiety-like behavior in mice.
Authors: Lee S; The Fleischer Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, Bronx, NY, USA.; Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA., Hwang J; The Fleischer Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, Bronx, NY, USA.; Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA., Jo YH; The Fleischer Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, Bronx, NY, USA. young-hwan.jo@einsteinmed.edu.; Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA. young-hwan.jo@einsteinmed.edu.; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA. young-hwan.jo@einsteinmed.edu.; Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, USA. young-hwan.jo@einsteinmed.edu.
Source: Translational psychiatry [Transl Psychiatry] 2026 May 11; Vol. 16 (1). Date of Electronic Publication: 2026 May 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2158-3188
DOI:10.1038/s41398-026-04074-7