Targeting the GSK-3β/mTOR axis to overcome chemoresistance in gestational choriocarcinoma: molecular mechanisms and therapeutic opportunities.

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Title: Targeting the GSK-3β/mTOR axis to overcome chemoresistance in gestational choriocarcinoma: molecular mechanisms and therapeutic opportunities.
Authors: Al-Hajeili M; Department of Medicine, King Abdulaziz University, Kingdom of Saudi Arabia, Jeddah, 23624, Saudi Arabia. Marwan.alhajeili@gmail.com., Al-Kuraishy HM; Department of Clinical Pharmacology and Medicine, College of Medicine, Al-Mustansiriyah University, Baghdad, Iraq., Abdelaziz AM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Sinai University- Arish Branch, Arish, 45511, Egypt. ahmed.abdelaziz@su.edu.eg., El-Saber Batiha G; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhur University, Damanhur, AlBeheira, 22511, Egypt. dr_gaber_batiha@vetmed.dmu.edu.eg.
Source: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2026 May 12; Vol. 96 (1). Date of Electronic Publication: 2026 May 12.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-0843
DOI:10.1007/s00280-026-04896-8